| Identification | More | [Name]
2-CHLORO-1,1,1-TRIFLUOROETHANE | [CAS]
75-88-7 | [Synonyms]
1，1，1-Trifluoro-2-chloroethane
1,1,1-TRIFLUORO CHLOROETHANE
1-CHLORO-2,2,2-TRIFLUOROETHANE
2,2,2-TRIFLUOROETHYL CHLORIDE
2-CHLORO-1,1,1-TRIFLUOROETHANE
Chlorotrifluoro ethane
FC-133A
HCFC-133A
TRIFLUOROETHYL CHLORIDE
(Chloromethyl)trifluoromethane
1,1,1-Trifluor-2-chlorethan
1,1,1-Trifluorethylchlorid
1,1,1-Trifluoroethyl chloride
1,1,1-trifluoroethylchloride
1-Chlor-2,2,2-trifluorethan
1-Chloro-2,2,2-trifluoroethene
2,2,2-Trifluorochloroethane
2-chloro-1,1,1-trifluoro-ethan
2-chloro-1,1,1-trifluoroethane(hcfc-133a)
CF3CH2Cl | [EINECS(EC#)]
200-912-0 | [Molecular Formula]
C2H2ClF3 | [MDL Number]
MFCD00039361 | [Molecular Weight]
118.49 | [MOL File]
75-88-7.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R59:Dangerous for the ozone layer. | [Safety Statements ]
S9:Keep container in a well-ventilated place .
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S59:Refer to manufacturer/supplier for information on recovery/recycling . | [RIDADR ]
1983 | [Hazard Note ]
Irritant | [TSCA ]
T | [HazardClass ]
2.2 | [Safety Profile]
A poison by inhalation.
Experimental reproductive effects.
Questionable carcinogen with experimental
carcinogenic data. When heated to
decomposition it emits toxic fumes of F-. | [Hazardous Substances Data]
75-88-7(Hazardous Substances Data) | [Toxicity]
LCLo inhalation in guinea pig: 33000ppm/5H |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
2,2,2-Trifluoroethyl trifluoromethanesulfonate-->Trifluoromethanesulfonyl chloride-->2,2,2-Trifluoroethanol-->N-nitrosobis(2,2,2-trifluoroethyl)amine-->2,2,2-TRIFLUOROETHYLAMINE-->BIS(2,2,2-TRIFLUOROETHYL)AMINE | [Preparation Products]
1,1,1-Trichlorotrifluoroethane-->2-CHLORO-1,1-DIFLUOROETHYLENE-->Halothane-->1,1,1,2-Tetrafluoroethane |
| Hazard Information | Back Directory | [General Description]
1-CHLORO-2,2,2-TRIFLUOROETHANE(75-88-7) is a colorless, odorless gas. 1-CHLORO-2,2,2-TRIFLUOROETHANE(75-88-7) is shipped as a liquid under its own vapor pressure. Contact with the liquid may cause frostbite to unprotected skin. 1-CHLORO-2,2,2-TRIFLUOROETHANE(75-88-7) can asphyxiate by the displacement of air. Exposure of the container to fire or heat can cause 1-CHLORO-2,2,2-TRIFLUOROETHANE(75-88-7) to rupture violently and rocket. | [Reactivity Profile]
1-CHLORO-2,2,2-TRIFLUOROETHANE is chemically inert in many situations, but can react violently with strong reducing agents such as the very active metals and the active metals. Undergoes oxidation with strong oxidizing agents and under extremes of temperature. | [Health Hazard]
Vapors may cause dizziness or asphyxiation without warning. Vapors from liquefied gas are initially heavier than air and spread along ground. Contact with gas or liquefied gas may cause burns, severe injury and/or frostbite. Fire may produce irritating, corrosive and/or toxic gases. | [Fire Hazard]
Some may burn but none ignite readily. Containers may explode when heated. Ruptured cylinders may rocket. | [Chemical Properties]
HCFC 133a is odorless with poor warning properties. | [Uses]
HCFC133a is a nonisolated intermediate in the production of
halothane. | [Definition]
ChEBI: 2-Chloro-1,1,1-trifluoroethane is an organofluorine compound. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 70, p. 758, 1948 DOI: 10.1021/ja01182a096 | [Carcinogenicity]
HCFC 133a was evaluated in a
carcinogenesis screening study using Wistar-derived
rats. The rats were given daily intubations of 300mg HCFC
of body weight in corn oil for 52 weeks and held for a total of
125 weeks. In the males, there was a reduction in body
weight gain and testicular size, also there was an increase
in Leydig cell tumors and arrest of spermatogenesis.
In the females, there was an increased incidence of uterine
carcinomas. |
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