| Identification | Back Directory | [Name]
Deoxynojirimycin hydrochloride | [CAS]
73285-50-4 | [Synonyms]
DNJ
DNM
DNM1
1-DNJ
AT 2220
DNJ, HCL
B-dynamin
Dynamin BREDNM19
DEOXYNOJIRIMICIN
DEOXYNOJIRIMYCIN
DNJ Hydrochloride
DeoxynojirimycinHCl
DNJ，1-Deoxynojirimycin
Moranoline Hydrochloride
Duvoglustat Hydrochloride
DEOXYNOJIRIMYCIN HYDROCHLORIDE
1-DEOXYNOJIRIMYCIN HYDROCHLORIDE
(+)-1-DEOXYNOJIRIMYCIN HYDROCHLORIDE
1,5-DIDEOXY-1,5-IMINO-D-SORBITOL HYDROCHLORIDE
1,5-DIDEOXY-1,5-IMINO-D-GLUCITOL HYDROCHLORIDE
(2R,3R,4R,5S)-2-(HYDROXYMETHYL)-3,4,5-PIPERIDINETRIOL
Anti-Dynamin-1, C-Terminal antibody produced in rabbit
(2R,3R,4R,5S)-2-(hydroxyMethyl)piperidine-3,4,5-triol hydrochloride
(2R,3R,4R,5S)-2-(HydroxyMethyl)-3,4,5-piperidinetriol Hydrochloride
3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, hydrochloride, (2R,3R,4R,5S)-
1-Deoxynojirimycin hydrochloride,1,5-Dideoxy-1,5-imino-D-sorbitol hydrochloride | [Molecular Formula]
C6H13NO4 | [MDL Number]
MFCD00063474 | [MOL File]
73285-50-4.mol | [Molecular Weight]
163.17 |
| Chemical Properties | Back Directory | [Appearance]
White Crystalline Solid | [Melting point ]
195-196°C | [storage temp. ]
2-8°C
| [solubility ]
Water (Slightly) | [form ]
Powder | [color ]
White | [Water Solubility ]
Soluble in water at 20mg/ml | [BRN ]
3563225 | [Stability:]
Hygroscopic | [CAS DataBase Reference]
73285-50-4 |
| Hazard Information | Back Directory | [Chemical Properties]
White Crystalline Solid | [Uses]
Deoxynojirimycin inhibits mammalian glucosidase 1. As well, it inhibits intestinal and lysosmal alpha-glucosidases, beta-glucosidase from sweet almonds, pancreatic alpha-amylase and amyloglucosidase. | [Uses]
natural chitin synthase inhibitor | [Description]
1-Deoxynojirimycin (1-DNJ) is an iminosugar that has been found in M. alba (mulberry) leaves and has diverse biological activities.1,2,3,4,5,6 It inhibits the activities of α- and β-glucosidase (IC50s = 35 and 71 μM, respectively).2 1-DNJ (5 mM) reduces the formation of N-linked complex oligosaccharides in IEC-6 cells.3 It inhibits HIV-1 envelope-mediated membrane fusion in CEM cells when used at a concentration of 2 mM.4 1-DNJ (1-100 μg/ml) reduces the invasion and migration of B16/F10 mouse melanoma cells.5 It improves glucose and insulin tolerance in db/db mice when administered intravenously at doses ranging from 20 to 80 mg/kg per day for four weeks.6 | [General Description]
Specific glucosidase inhibitor, including trimming glucosidases I and II, that sequentially removes the three glucose residues from precursor Glc3Man9GlcNAc2 in N-linked glycan biosynthesis. | [Biochem/physiol Actions]
Product does not compete with ATP. | [storage]
Store at -20°C |
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