| Identification | Back Directory | [Name]
REMOXIPRIDE HYDROCHLORIDE | [CAS]
73220-03-8 | [Synonyms]
CV236900
(s)-(-)-d
(-)-fla732
REMOXIPRIDE HYDROCHLORIDE
(S)-ReMoxipride Hydrochloride
Remoxipride Hydrochloride (anhydrous)
3-bromo-2,6-dimethoxy-n-(1-ethyl-2-pyrrolidinylmethyl)-benzamidhydrochlori
S-(-)-3-BROMO-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2,6-DIMETHOXYBENZAMIDE HCL
(s)-(-)-2-((3-bromo-2,6-dimethoxybenzamido)methyl)-1-ethylpyrrolidinehydroch
(s)-(-)-3-bromo-2,6-dimethoxy-n-(1-ethyl-2-pyrrolidinylmethyl)benzamidehydro
(-)-(S)-3-Brom-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2,6-dimethoxybenzamide hydrochloride
(S)-(-)-3-BROMO-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]2,6-DIMETHOXYBENZAMIDE HYDROCHLORIDE
(S)-(-)-3-BROMO-N-[(1-ETHYL-2-PYRROLIDINYL0METHYL]2,6-DIMETHOXYBENZAMIDE HYDROCHLORIDE | [Molecular Formula]
C16H24BrClN2O3 | [MDL Number]
MFCD01743944 | [MOL File]
73220-03-8.mol | [Molecular Weight]
407.73 |
| Chemical Properties | Back Directory | [Melting point ]
168-169 °C | [storage temp. ]
Store at RT | [solubility ]
Chloroform (Sparingly), Water (Slightly, Sonicated) | [form ]
White solid. | [color ]
White to Off-White | [Water Solubility ]
Soluble to 100 mM in water | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
Specific dopamine D2-receptor antagonist. Antipsychotic. | [Biological Activity]
Standard D 2 receptor antagonist showing some selectivity over D 3 and D 4 receptors (K i values are ~ 300, ~ 1600, and ~ 2800 nM for D 2 , D 3 and D 4 receptors respectively). In vivo remoxipride is an antipsychotic which does not cause extrapyramidal side effects and is 50-fold more potent than sulpiride in antagonising the effects of apomorphine in the rat. |
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