| Identification | More | [Name]
Bromoacetaldehyde dimethyl acetal | [CAS]
7252-83-7 | [Synonyms]
2,2-DIMETHOXYETHYL BROMIDE
2-BROMO-1,1-DIMETHOXYETHANE
BADA
BADMA
BROMOACETALDEHYDE DIMETHYL ACETAL
1-Bromo-2,2-dimethoxyethane
2,2-Dimethoxybromoethane
2-bromo-1,1-dimethoxy-ethan
2-Bromoacetaldehyde dimethyl acetal
Acetaldehyde, bromo-, dimethyl acetal
Dimethylbromoacetal
BROMOACETALDEHYDE DIMETHYL ACETAL, STAB.
BROMOACETALDEHYDE DIETHYL ACETAL(2-BROMIDE-1,1-DIETHOXYETHANE)
2-BROMO-1,1-DIMETHYOXYERHANE
BromoacetaldehydeDimethylacetal(Stabilized)97%
2-BROMO-1,1-DIMETHYLETHANE
Bromoacetaldehyde dimethyl acetal, stabilized, 97%
BROMOACETALDEHYDE DIMETHYL ACETAL , STABILIZED WITH POTASSIUM CARBONATE
BROMOACETALDEHYDE DIMETHYL ACETAL (BADA)
Bromoacetaldehyde dimethyl acetal, 97+%, stab. with potassium carbonate | [EINECS(EC#)]
230-669-6 | [Molecular Formula]
C4H9BrO2 | [MDL Number]
MFCD00000213 | [Molecular Weight]
169.02 | [MOL File]
7252-83-7.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R10:Flammable.
R36:Irritating to the eyes.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/39:Wear suitable protective clothing and eye/face protection .
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
UN 1989 3/PG 3
| [WGK Germany ]
3
| [F ]
8-9-21 | [TSCA ]
Yes | [HazardClass ]
3 | [PackingGroup ]
III | [HS Code ]
29110000 |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
1,2-Dibromo-1-ethoxyethane-->Paraldehyde | [Preparation Products]
1-BENZOTHIOPHENE-5-CARBOXYLIC ACID-->BENZOFURAN-5-BORONIC ACID-->2-(1-BENZOTHIOPHEN-5-YL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE-->(5-BROMO-3-BENZO[B]THIENYL)METHANOL-->(5-CHLORO-1-BENZOTHIOPHEN-3-YL)METHANOL-->5-BROMOBENZO[B]THIOPHENE-3-CARBOXYLIC ACID-->5-CHLORO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID-->1-BENZOTHIOPHENE-5-CARBONYL CHLORIDE-->1-(1,3-DIOXOLAN-2-YLMETHYL)PIPERAZINE-->1-(5-BROMO-1-BENZOTHIEN-3-YL)ETHANONE-->3-Acetyl benz[b]thiophene-->1-(5-CHLOROBENZO[B]THIOPHEN-3-YL)ETHANONE-->5-CHLOROBENZOTHIOPHENE-->7-CYANO-BENZO[B]THIOPHENE-->2,2'-METHYLIMINOBIS-(ACETALDEHYDE DIMETHYL ACETAL)-->6,8-DIBROMOIMIDAZO[1,2-A]PYRAZINE-->Methoxyethene-->Oxazole-2-amine-->Benzene, 1-chloro-4-[(2,2-dimethoxyethyl)thio]- |
| Questions And Answer | Back Directory | [Description]
2-Bromo-1,1-dimethoxyethane (Bromoacetaldehyde dimethyl acetal) is used in the synthesis of 2,3-O-acetal via reaction with 2,3-diol in the presence of 10-camphorsulphonic acid (CSA). 2-bromo-1,1-dimethoxyethane was used to react with 4-hydroxylbenzaldehyde, and finally aldehyde substituted prodrug was generated by TFA-mediated deacetalization. It is widely used in chemistry for the synthesis of a variety of antibiotics (including erythromycin and cephalosporins) and other drugs. It is an important and highly reactive bifunctional compound with a good leaving group and a masked aldehyde function. It can be used as a starting material in a variety of reactions to provide N-alkylated compounds, lactams, aldehydes, oximes, azides, and acyclic di-/polyselenides.
| [Reference]
Gotkowska, Joanna. "Bromoacetaldehyde Diethyl Acetal." Synlett26.15(2015):2185-2186.
|
| Hazard Information | Back Directory | [Chemical Properties]
clear colourless to light yellow liquid | [Uses]
2-Bromo-1,1-dimethoxyethane (Bromoacetaldehyde dimethyl acetal) was used in the synthesis of 2,3-O-acetal via reaction with 2,3-diol in the presence of 10-camphorsulphonic acid (CSA). 2-bromo-1,1-dimethoxyethane was used to react with 4-hydroxylbenzaldehyde, and finally aldehyde substituted prodrug was generated by TFA-mediated deacetalization. |
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