| Identification | More | [Name]
3-Acetylindole | [CAS]
703-80-0 | [Synonyms]
1-(1H-INDOL-3-YL)ETHANONE
3-ACETYL-1-BENZAZOLE
3-ACETYL-2,3-BENZOPYRROLE
3-ACETYLINDOLE
3-INDOLYL METHYL KETONE
AKOS BBS-00004490
IFLAB-BB F1727-0313
TIMTEC-BB SBB003977
3-Acetyl-1H-indole
Acetyl-3-indole
Ketone, indol-3-yl methyl
ketone,indol-3-ylmethyl
indol-3-yl methyl ketone
3-ACETYLINDOLE PRACTICAL GRADE
Ethanone, 1-(1H-indol-3-yl)-(9CI)
Ethanone, 1-(1H-indol-3-yl)-
3-Acetylindole ,98% | [EINECS(EC#)]
211-875-5 | [Molecular Formula]
C10H9NO | [MDL Number]
MFCD00005626 | [Molecular Weight]
159.18 | [MOL File]
703-80-0.mol |
| Chemical Properties | Back Directory | [Appearance]
yellow to light brown powder | [Melting point ]
188-192 °C (lit.) | [Boiling point ]
284.68°C (rough estimate) | [density ]
1.1202 (rough estimate) | [refractive index ]
1.6070 (estimate) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
DMSO; Dichloromethane; Methanol; | [form ]
Powder | [pka]
15.38±0.30(Predicted) | [color ]
Yellow to light brown | [Detection Methods]
HPLC,NMR | [BRN ]
122579 | [CAS DataBase Reference]
703-80-0(CAS DataBase Reference) | [NIST Chemistry Reference]
Ethanone, 1-(1h-indol-3-yl)-(703-80-0) |
| Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [RTECS ]
OB4520000
| [HazardClass ]
IRRITANT | [HS Code ]
29339990 |
| Hazard Information | Back Directory | [Chemical Properties]
yellow to light brown powder | [Uses]
Reactant for preparation of:
- Indole derivatives as antitumor agents
- Endothelin-1 antagonists
- Oncrasin-1 derivatives as inhibitors of the C-terminal domain of RNA polymerase II with antitumor activities
- Inhibitors of hepatitis C NS3/4A serine protease
- Antibacterial agens against MDR Staphylococcus aureus strains
- Antimalarial agents
- Anti-bovine viral diarrhea virus (BVDV) agents
- HIV-1 integrase inhibitors
- Inhibitors of NF-κB transcription regulation related to TNF-α cytokine release
| [Uses]
Reactant for preparation of:• ;Indole derivatives as antitumor agents1• ;Endothelin-1 antagonists2• ;Oncrasin-1 derivatives as inhibitors of the C-terminal domain of RNA polymerase II with antitumor activities3• ;Inhibitors of hepatitis C NS3/4A serine protease4• ;Antibacterial agens against MDR Staphylococcus aureus strains5• ;Antimalarial agents6• ;Anti-bovine viral diarrhea virus (BVDV) agents7• ;HIV-1 integrase inhibitors8• ;Inhibitors of NF-κB transcription regulation related to TNF-α cytokine release9 | [Purification Methods]
Recrystallise the indole from MeOH or *C6H6 containing a little EtOH. The phenylureido derivative has m 154o. [Baker J Chem Soc 461 1946, Beilstein 21/8 V 297.] |
|
|