| Identification | More | [Name]
3-Chlorophenyl piperazine | [CAS]
6640-24-0 | [Synonyms]
1-(3-CHLOROPHENYL)PIPERAZINE
1-(3-CHLORPHENYL)-PIPERAZINE
3-chlorophenyl piperazine
AKOS BBS-00003580
MCPP
N-(3-CHLOROPHENYL)PIPERAZINE
RARECHEM AH CK 0071
TIMTEC-BB SBB003579
1-(3-CHLOROPHENYL)PIPERAZINE HBR
1,3ChlorofenylPiperazine
3-Chlorophenyl-1-Piperazine
CHLOROPHENYLPIPERAZINE
1-(3-Chlorophenyl)piperazine 97%
1-(3-CHLOROPHENYL)PIPERAZINE (MCPP)
4-(3-Chlorophenyl)piperazine
N-(m-Chlorophenyl)piperazine
NSC 49307
Piperazine, 1-(3-chlorophenyl)-
1-(3-Chlorophenyl)piperazine ,98％
m-Chlorophenylpiperazine | [EINECS(EC#)]
229-654-7 | [Molecular Formula]
C10H13ClN2 | [MDL Number]
MFCD00040732 | [Molecular Weight]
196.68 | [MOL File]
6640-24-0.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless to light yellow oily liquid | [Melting point ]
210-214°C | [Boiling point ]
105 °C | [density ]
1.193 | [refractive index ]
1,598-1,600 | [storage temp. ]
-20°C Freezer, Under Inert Atmosphere | [pka]
8.85±0.10(Predicted) | [Usage]
It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone. The metabolite m-C | [Detection Methods]
GC,NMR | [CAS DataBase Reference]
6640-24-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S36:Wear suitable protective clothing . | [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Hazard]
A poison. | [Chemical Properties]
clear colorless to light yellow oily liquid | [Uses]
It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone (1,2,3). The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone. | [Uses]
It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone. The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone. | [Definition]
ChEBI: A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone. |
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