| Identification | More | [Name]
Triisopropylsilane | [CAS]
6485-79-6 | [Synonyms]
(ME2CH)3SIH
SILANE IP3H
TIPS
TIS
TRIISOPROPYLSILANE
Tris-isopropylsilane
Triisopropylsilane (TIPS)
Triisopropylsilane [Cas#
tripropan-2-ylsilane
Triisopropylhydrosilane
Triisopropylsilane ,97% | [EINECS(EC#)]
464-880-1 | [Molecular Formula]
C9H22Si | [MDL Number]
MFCD00009657 | [Molecular Weight]
158.36 | [MOL File]
6485-79-6.mol |
| Chemical Properties | Back Directory | [Appearance]
Clear colorless liquid | [Boiling point ]
84-86 °C/35 mmHg (lit.) | [density ]
0.773 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.434(lit.)
| [Fp ]
99 °F
| [storage temp. ]
Store at RT. | [form ]
liquid | [color ]
colorless | [Specific Gravity]
0.773 | [Water Solubility ]
Immiscible with water. | [Hydrolytic Sensitivity]
3: reacts with aqueous base | [Sensitive ]
Moisture Sensitive | [Detection Methods]
GC,NMR | [BRN ]
1733718 | [InChIKey]
YDJXDYKQMRNUSA-UHFFFAOYSA-N | [CAS DataBase Reference]
6485-79-6(CAS DataBase Reference) | [Storage Precautions]
Moisture sensitive |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R10:Flammable.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection .
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
UN 1993 3/PG 3
| [WGK Germany ]
3
| [F ]
10-21 | [TSCA ]
No | [HazardClass ]
3 | [PackingGroup ]
III | [HS Code ]
29319090 |
| Hazard Information | Back Directory | [Chemical Properties]
Clear colorless liquid | [Uses]
Selective silylation of primary hydroxy groups in the presence of secondary alcohol. | [Uses]
The bulky isopropyl groups (vs. ethyl) allow for more selective reductions, e.g., beta-selective reduction of anomeric C-phenyl ketals, but do not diminish their activity (e.g. in the copper triflate catalyzed reductive etherification of trimethylsilyl ethers). | [Application]
Very sterically-hindered silane. Used as a cation
scavenger in the deprotection of peptides. |
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