Identification | More | [Name]
Ethoxyacetic acid | [CAS]
627-03-2 | [Synonyms]
ETHOXYACETIC ACID GLYCOLIC ACID ETHYL ETHER O-ETHYLGLYCOLIC ACID 2-Ethoxyacetic acid 2-ethoxyaceticacid Aceticacid,ethoxy- ethoxy-aceticaci Ethoxyethanoicacid Ethylglycolicacid Glycollicacidethylether α-Ethylglycollicacid Ethoxyaceticacid,97% Ethoxyacetic ethyloglycolic acid Ethyloxyacetic acid Glycolic ethyl ether | [EINECS(EC#)]
210-978-2 | [Molecular Formula]
C4H8O3 | [MDL Number]
MFCD00004310 | [Molecular Weight]
104.1 | [MOL File]
627-03-2.mol |
Safety Data | Back Directory | [Hazard Codes ]
C,Xi | [Risk Statements ]
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 3265 8/PG 2
| [WGK Germany ]
3
| [RTECS ]
AH3600000
| [Hazard Note ]
Irritant | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29189900 | [Safety Profile]
Experimental
reproductive effects. When heated to
decomposition it emits acrid smoke and
irritating fumes. |
Hazard Information | Back Directory | [General Description]
Liquid. | [Reactivity Profile]
An ether and organic acid. Carboxylic acids donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt. Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water. Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions. The pH of solutions of carboxylic acids is therefore less than 7.0. Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt. Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide. Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat. Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents. These reactions generate heat. | [Air & Water Reactions]
Water soluble. | [Health Hazard]
ACUTE/CHRONIC HAZARDS: This compound is corrosive. | [Fire Hazard]
This chemical is combustible. | [Chemical Properties]
liquid | [Uses]
Ethoxyacetic acid is used to evaluate toxicity in embryonic stem cell test in mice. It finds application as a biomarker of exposure to alkyl-substituted ethylene glycols and other aliphatic ethers. It is used as a precursor to prepare ethoxy-acetic acid ethoxymethyl ester. | [Definition]
ChEBI: Ethoxyacetic acid is a carboxylic acid. | [Biochem/physiol Actions]
Ethoxyacetic acid induces testicular toxicity in rats in vivo . |
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