| Identification | Back Directory | [Name]
Cyclomulberrochromene | [CAS]
62596-34-3 | [Synonyms]
Cyclomorusin A
Cyclomulberrochromene
6,11-Dihydroxy-3,3-dimethyl-8-(2-methyl-1-propenyl)-3H,7H,8H-bis[1]benzopyrano[4,3-b:6',5'-e]pyran-7-one
3H,7H,8H-Bis[1]benzopyrano[4,3-b:6',5'-e]pyran-7-one, 6,11-dihydroxy-3,3-dimethyl-8-(2-methylpropen-1-yl)- | [Molecular Formula]
C25H22O6 | [MOL File]
62596-34-3.mol | [Molecular Weight]
418.44 |
| Chemical Properties | Back Directory | [Melting point ]
233-234 °C | [Boiling point ]
659.9±55.0 °C(Predicted) | [density ]
1.42±0.1 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder | [pka]
6.96±0.60(Predicted) | [color ]
Yellow |
| Hazard Information | Back Directory | [Uses]
Cyclomorusin (Cyclomorusin A; Cyclomulberrochromene) is a prenylflavonoid with antiplatelet activity. Cyclomorusin also inhibits markedly collagen-induced platelet aggregation[1]. | [Definition]
ChEBI: An extended flavonoid that is cyclomulberrin in which the hydroxy group at position 10 has undergone oxidative cyclisation to position 3 of the 3-methylbut-2-en-1-yl substituent, with migration of the double bond into conjugation with the aromatic ring. It
is a moderate inhibitor of acetylcholinesterase (IC50 = 16.2 - 36.6 muM), and a strong inhibitor of platelet-activating factor (PAF; 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) induce
platelet aggregation. | [target]
NO | NOS | [References]
[1] Lin CN, et al. Antiplatelet activity of some prenylflavonoids. Biochem Pharmacol. 1993 Jan 26;45(2):509-12. PMID:8435100 |
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