| Identification | More | [Name]
5-Methylindole | [CAS]
614-96-0 | [Synonyms]
5-METHYL-1H-INDOLE
5-METHYLINDOLE
AKOS JY2082955
1H-Indole,5-methyl-
5-Methylindol
Indole, 5-methyl-
5-Methylindole,99%
5-METLYLINDOLE
5-METHYLINDOLE CRYSTALLINE
5-METHYLHEX-3-EN-2-ONE | [EINECS(EC#)]
210-400-9 | [Molecular Formula]
C9H9N | [MDL Number]
MFCD00005680 | [Molecular Weight]
131.17 | [MOL File]
614-96-0.mol |
| Chemical Properties | Back Directory | [Appearance]
white to slightly beige crystalline solid | [Melting point ]
60-62 °C (lit.) | [Boiling point ]
100°C/3mm | [density ]
1.0202 | [refractive index ]
1.6070 (estimate) | [Fp ]
100°C/3mm | [storage temp. ]
Keep Cold | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Crystalline Solid | [pka]
17.17±0.30(Predicted) | [color ]
White to slightly beige | [Water Solubility ]
Insoluble in water. | [Sensitive ]
Light Sensitive | [BRN ]
2228 | [LogP]
2.680 | [CAS DataBase Reference]
614-96-0(CAS DataBase Reference) | [NIST Chemistry Reference]
1H-Indole, 5-methyl-(614-96-0) | [EPA Substance Registry System]
614-96-0(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S24/25:Avoid contact with skin and eyes . | [RIDADR ]
UN3335 | [WGK Germany ]
3
| [Hazard Note ]
Light Sensitive/Keep Cold | [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Chemical Properties]
white to slightly beige crystalline solid | [Uses]
5-Methylindole is used as reactant for preparation of pharmaceutically active 2-oxo-1-pyrrolidine analogues, potential anticancer immunomodulators, IL2-inducible T-cell kinase (ITK) inhibitors and CRTh2 antagonists. | [Uses]
5-Methylindole is used in the synthesis of novel protein kinase inhibitors. | [Synthesis Reference(s)]
Synthesis, p. 1036, 1982 DOI: 10.1055/s-1982-30054 | [General Description]
The binding of 5-methylindole (inducer) to the Escherichia coli trp repressor has been studied. The mass analyzed threshold ionization spectra of jetcooled 5-methylindole (5MI) has also been studied. |
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