| Identification | Back Directory | [Name]
Glycerol phenylbutyrate | [CAS]
611168-24-2 | [Synonyms]
Ravicti
HPN-100
Glycerol phenylbutryate
Glycerol phenylbutyrate
glyceryl tri-(4-phenylbutyrate)
Propane-1,2,3-triyl tris(4-phenylbutanoate)
BENZENEBUTANOIC ACID, 1,2,3-PROPANETRIYL ESTER
2,3-bis(4-phenylbutanoyloxy)propyl4-phenylbutanoate
Benzenebutanoic acid, 1,1',1''-(1,2,3-propanetriyl) ester | [Molecular Formula]
C33H38O6 | [MDL Number]
MFCD28016960 | [MOL File]
611168-24-2.mol | [Molecular Weight]
530.65 |
| Chemical Properties | Back Directory | [Boiling point ]
621.2±45.0 °C(Predicted) | [density ]
1.131±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:150.0(Max Conc. mg/mL);282.67(Max Conc. mM)
Ethanol:50.0(Max Conc. mg/mL);94.22(Max Conc. mM) | [form ]
Oil | [color ]
Colourless |
| Hazard Information | Back Directory | [Uses]
Tri(4-phenylbutyryl)glycerol is a drug that is currently under development for treatment of urea cyclic disorders (UCDs). It works by preventing the harmful buildup of ammonia in the body. | [Definition]
ChEBI: Glycerol phenylbutyrate is a triglyceride. | [Biological Activity]
Glycerol phenylbutyratea triacylglycerolis a prodrug of ER stress inhibitor 4-phenylbutyric acid (PBA). Glycerol phenylbutyrate is a nitrogen-binding agent approved for the chronic management of adult and pediatric patients (≥2 years of age) with urea cycle disorders (UCDs) who cannot be managed by dietary protein restriction and/or amino acid supplementation alone. |
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