| Identification | More | [Name]
DULCITOL | [CAS]
6051-87-2 | [Synonyms]
5,6-BENZOFLAVONE
BETA-NAPHTHOFLAVONE
BETA-NF
B-NAPHTHOFLAVANONE
B-NAPHTHOFLAVONE
BNF
DULCITE
DULCITOL
GALACTITOL
MELAMPYRITE
NAPHTHOFLAVANONE, B-
NAPHTHOFLAVONE, B-
1-b)pyran-1-one,3-phenyl-1h-naphtho(
1H-Naphtho[2,1-b]pyran-1-one,3-phenyl-
3-Phenyl-1H-benzo[f]chromen-1-one
3-Phenyl-1H-naphtho(2,1-b)pyran-1-one
3-Phenyl-1H-naphtho[2,1-b]pyran-1-one
3-Phenyl-benzo[f]chromen-1-one
β-Naphthoflavon
BETA-NAPHTHOFLAVONE, 98+% | [EINECS(EC#)]
227-958-4 | [Molecular Formula]
C6H14O6 | [MDL Number]
MFCD00064288 | [Molecular Weight]
182.17 | [MOL File]
6051-87-2.mol |
| Chemical Properties | Back Directory | [Appearance]
SLIGHTLY BEIGE CRYSTALLINE POWDER | [Melting point ]
164-166 °C (lit.) | [Boiling point ]
275-280 °C (1 mmHg) | [density ]
1.1382 (rough estimate) | [refractive index ]
1.5510 (estimate) | [storage temp. ]
2-8°C
| [solubility ]
Chloroform (Slightly), Methanol (Slightly, Heated) | [form ]
Crystalline Powder | [color ]
yellow to tan
| [BRN ]
18991 | [LogP]
5.003 (est) | [CAS DataBase Reference]
6051-87-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi,C,F | [Risk Statements ]
R22:Harmful if swallowed.
R34:Causes burns.
R11:Highly Flammable. | [Safety Statements ]
S24/25:Avoid contact with skin and eyes .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S16:Keep away from sources of ignition-No smoking . | [WGK Germany ]
3
| [RTECS ]
QL6200000
| [F ]
3-10 | [Hazard Note ]
Irritant | [HS Code ]
29329900 |
| Hazard Information | Back Directory | [Chemical Properties]
SLIGHTLY BEIGE CRYSTALLINE POWDER | [Uses]
beta-Naphthoflavone is a Cytochrome P450 enzyme system inducer. It can also be used in biological study of novel dual-color luciferase reporter assay for simultaneous detection of estrogen and aryl hydrocarbon receptor activation. | [Definition]
ChEBI: An extended flavonoid resulting from the formal fusion of a benzene ring with the f side of flavone. | [General Description]
β-Naphthoflavone is a polyaromatic hydrocarbon. | [Biochem/physiol Actions]
β-Naphthoflavone (BNF) is an exogenous ligand for aryl hydrocarbon receptor (AhR) in humans. It is an inducer of phase I detoxification enzymes (CYPs) and phase II enzymes (UDP-GTs) and NAD(P)H-dependent quinone oxyreductase-1(NQO1). It also induces cytochrome P450 (Cyp1a). BNF represses the expression of Duchenne muscular dystrophy gene, dystrophin (Dp)71 by altering the binding of the transcription factors. |
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