| Identification | Back Directory | [Name]
CARNOSOL | [CAS]
5957-80-2 | [Synonyms]
CARNOSOL
CARNOSOL(RG)
CARNOSOL USP/EP/BP
Carnosol, froM RoseMarinus officinalis
Carnosol, 98%, from Rosemarinus officinalis
1,3,4,9,10AS-HEXAHYDRO-5,6-DIHYDROXY-1,1-DIMETHYL-7-ISO-PROPYL-2H-9S,4AR-(EPOXYMETHANO)PHENANTHREN-12-ONE
1,3,4,9,10,10AS-HEXAHYDRO-5,6-DIHYDROXY-1,1-DIMETHYL-7-ISO-PROPYL-2H-9S,4AR-(EPOXYMETHANO)PHENANTHREN-12-ONE
1,2,3,4,4A,9,10,10AS-OCTAHYDRO-5,6-DIHYDROXY-1,1-DIMETHYL-7-ISOPROPYL-9S, 4AR (EPOXYMETHANO)PHENANTHREN-12-ONE
2H-9,4a-(Epoxymethano)phenanthren-12-one, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR,9S,10aS)- | [Molecular Formula]
C20H26O4 | [MDL Number]
MFCD02752467 | [MOL File]
5957-80-2.mol | [Molecular Weight]
330.42 |
| Chemical Properties | Back Directory | [Melting point ]
240～242℃ | [Boiling point ]
524.8±50.0 °C(Predicted) | [density ]
1.26±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Store in freezer, under -20°C | [solubility ]
DMSO:66.0(Max Conc. mg/mL);199.74(Max Conc. mM) | [form ]
neat | [pka]
8.91±0.40(Predicted) | [color ]
White | [LogP]
2.832 (est) |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
Carnosol is a phytopolyphenol found in Rosemary that functions as an antioxidant, antimicrobial, & anticarcinogen. | [Definition]
ChEBI: Carnosol is a diterpenoid. | [Cytotoxicity]
IC50 (μg/mL): 65 (HL-60), 58 (K562), 50(Hep G2), 48 (MCF-7), 53 (MOLT-4)(Farimani et al. 2012)
IC50 (μg/mL): 61.46 (AGS) (Areche et al.2009)
IC50 (μg/mL): 2 (P388) (Aoyagi et al.2006)
IC50 (μg/mL): 1.19 (A2780), 3.30(SW1573), 8.59 (WiDr), 7.93 (T-47D),1.29 (HBL-100) (Guerrero et al. 2006). |
|
|