| Identification | More | [Name]
4-(Trimethylsilyl)-3-butyn-2-one | [CAS]
5930-98-3 | [Synonyms]
4-TRIMETHYLSILYL-3-BUTYN-2-ONE
TIMTEC-BB SBB009031
4-(Trimethysilyl)-3-butyn-2-one
4-(TRIMETHYLSILYL)-3-BUTYN-2-ONE 98%
4-trimethylsilylbut-3-yn-2-one | [EINECS(EC#)]
628-294-1 | [Molecular Formula]
C7H12OSi | [MDL Number]
MFCD00190212 | [Molecular Weight]
140.26 | [MOL File]
5930-98-3.mol |
| Chemical Properties | Back Directory | [Appearance]
clear slightly yellow liquid | [Melting point ]
99 °C | [Boiling point ]
156 °C(lit.)
| [density ]
0.854 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.442(lit.)
| [Fp ]
83 °F
| [storage temp. ]
Flammables area | [Specific Gravity]
0.854 | [Hydrolytic Sensitivity]
4: no reaction with water under neutral conditions | [CAS DataBase Reference]
5930-98-3(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R10:Flammable.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [RIDADR ]
UN 1224 3/PG 3
| [WGK Germany ]
3
| [HazardClass ]
3 | [PackingGroup ]
III | [HS Code ]
29319090 |
| Hazard Information | Back Directory | [Chemical Properties]
clear slightly yellow liquid | [Uses]
4-(Trimethylsilyl)-3-butyn-2-one (TMSB) has been used to investigate its asymmetric bioreduction to (S)-4-(trimethylsilyl)-3-butyn-2-ol {(S)-TMSBOL} by employing biocompatible water-immiscible ionic liquids (ILs). TMSB may be used for the synthesis of entecavir (BMS-200475). | [General Description]
4-(Trimethylsilyl)-3-butyn-2-one is a ketone. Its asymmetric bioreduction to enantiopure {(S)-TMSBOL in various hydrophilic ionic liquid (ILs) solvent systems has been reported. |
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