| Identification | More | [Name]
2-Quinolinol | [CAS]
59-31-4 | [Synonyms]
2-HYDROXYQUINOLINE
2-QUINOLINOL
2-QUINOLONE
CARBOSTYRIL
2(1h)-quinolinone
2(1H)-Quinolone
2-Quinoline
2-Quinolinol 50
2-quinolinone
alpha-Hydroxyquinoline
alpha-Quinolone
o-Aminocinnamic acid lactam
o-aminocinnamicacidlactam
2-Hydroxyquinoline99%
2-Hydroxyquinoline 99%
2(1H)-Quinoline
2-HYDROXYQUINOLINE (2-QUINOLINOL)
2-Quinolinol, Carbostyril
2-Oxo-1,2-dihydroquinoline
1,2-Dihydroquinolin-2-one | [EINECS(EC#)]
274-516-1 | [Molecular Formula]
C9H7NO | [MDL Number]
MFCD00006743 | [Molecular Weight]
145.16 | [MOL File]
59-31-4.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light purple or purple-brownish powder | [Melting point ]
198-199 °C (lit.) | [Boiling point ]
264.27°C (rough estimate) | [density ]
1.1555 (rough estimate) | [refractive index ]
1.4500 (estimate) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
alcohol: soluble(lit.) | [form ]
Powder | [pka]
-0.31, 11.76(at 20℃) | [color ]
White to light purple or purple-brownish | [Water Solubility ]
1.052g/L(20 ºC) | [Detection Methods]
HPLC | [Merck ]
14,1825 | [BRN ]
2855 | [CAS DataBase Reference]
59-31-4(CAS DataBase Reference) | [NIST Chemistry Reference]
2(1H)-Quinolinone(59-31-4) | [Storage Precautions]
Air sensitive;Store under nitrogen | [EPA Substance Registry System]
59-31-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R41:Risk of serious damage to eyes.
R37/38:Irritating to respiratory system and skin .
R22:Harmful if swallowed. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
S36:Wear suitable protective clothing . | [RIDADR ]
2811 | [WGK Germany ]
3
| [RTECS ]
FG7175000
| [Hazard Note ]
Harmful/Irritant | [TSCA ]
Yes | [HS Code ]
29334900 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light purple or purple-brownish powder | [Uses]
2-Hydroxyquinoline was used to obtain the design of the platinum(IV) complexes with intense bands shifted towards longer wavelengths. The Pt(IV) complexes are inert stable prodrugs that were photoactivated to produce Pt(II) species with promising anticancer activity. | [Definition]
ChEBI: A quinolone that is 1,2-dihydroquinoline substituted by an oxo group at position 2. | [Synthesis Reference(s)]
Synthesis, p. 739, 1975 DOI: 10.1055/s-1975-23918 | [General Description]
2-Hydroxyquinoline is a specific inhibitor of plaque paraoxonase1 (PON1). | [Purification Methods]
Crystallise it from MeOH. It has m 200-201o after sublimation in a vacuum. The picrate has m 132o after crystallisation from Et2O. [Gibson et al. J Chem Soc 4340 1955, Beilstein 21 III/IV 1057, 21/8 V 217.] |
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