Identification | More | [Name]
6-Aminoquinoline | [CAS]
580-15-4 | [Synonyms]
6-AMINOQUINOLINE 6-QUINOLINAMINE 6-Quinolylamine AKOS 212-41 AKOS AUF01720 QUINOLIN-6-AMINE QUINOLIN-6-YLAMINE QUINOLINE, 6-AMINO- TIMTEC-BB SBB004130 6-Aminoquinoline,98% 6-Aminoquinoline, 99+% 6-AMINOQUINOLINE 99% | [EINECS(EC#)]
209-453-0 | [Molecular Formula]
C9H8N2 | [MDL Number]
MFCD00006803 | [Molecular Weight]
144.17 | [MOL File]
580-15-4.mol |
Chemical Properties | Back Directory | [Appearance]
Dark yellow to brown crystalline powder | [Melting point ]
115-119 °C (lit.) | [Boiling point ]
146 °C/0.3 mmHg (lit.) | [density ]
1.1148 (estimate) | [refractive index ]
1.7080 (estimate) | [Fp ]
146°C/0.3mm | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Chloroform, DMSO, Methanol | [form ]
Solid | [pka]
pK1: 5.63(+1) (20°C,μ=0.01) | [color ]
Pale Brown to Brown | [Water Solubility ]
Soluble in methanol, chloroform, ethanol, and benzene. Insoluble in water. | [Sensitive ]
Air Sensitive | [Detection Methods]
HPLC | [BRN ]
113320 | [CAS DataBase Reference]
580-15-4(CAS DataBase Reference) | [NIST Chemistry Reference]
6-Quinolinamine(580-15-4) | [Storage Precautions]
Store under nitrogen |
Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/38:Irritating to eyes and skin . R36/37/38:Irritating to eyes, respiratory system and skin . R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing . S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
2811 | [WGK Germany ]
3
| [F ]
2-10 | [HazardClass ]
IRRITANT, AIR SENSITIVE | [PackingGroup ]
III | [HS Code ]
29334900 |
Hazard Information | Back Directory | [Chemical Properties]
Dark yellow to brown crystalline powder | [Uses]
6-Aminoquinoline is used in the preparation of diaminopyrimidine derivatives as 5-HT4 receptor agonists. | [Purification Methods]
It is purified by column chromatography on a SiO2 column using CHCl3/MeOH (4:1) as eluent. It crystallises from *C6H6 or *C6H6/pet ether and is an irritant. The styphnate has m 239-240o (from EtOH) and m 242-243o (from aqueous Me2CO). [Barrett et al. J Chem Soc 50, 57 1953, Beilstein 22 III/IV 4681, 22/10 V 303.] |
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