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ChemicalBook--->CAS DataBase List--->568-73-0

568-73-0

568-73-0 Structure

568-73-0 Structure
IdentificationMore
[Name]

Tanshinone I
[CAS]

568-73-0
[Synonyms]

1,6,6-TRIMETHYL-6,7,8,9-TETRAHYDRO-PHENANTHRO[1,2-B]FURAN-10,11-DIONE
1,6-dimethyl-phenanthro[1,2-b]furan-10,11-dione
3,8,8-TRIMETHYL-8,9,10,11-TETRAHYDROPHENANTHRO[1,2-B]FURAN-1,2-DIONE
AKOS NCG1-0066
TANSHINONE I
TANSHINONE IIA
TANSHINONES IIA
TANSHINON I
Tanshinone
TANSHINONE I >98% BY HPLC FROM SALVIA MILTIORRHIZA B.
Phenanthro[1,2-b]furan-10,11-dione,1,6-dimethyl-
TanshinoneⅠ
[Molecular Formula]

C19H18O3
[MDL Number]

MFCD00238692
[Molecular Weight]

294.34
[MOL File]

568-73-0.mol
Chemical PropertiesBack Directory
[Melting point ]

233-234°C
[Boiling point ]

498.0±24.0 °C(Predicted)
[density ]

1.324±0.06 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Sealed in dry,2-8°C
[solubility ]

DMSO: soluble1mg/mL
[form ]

powder
[color ]

red
[LogP]

4.312 (est)
[CAS DataBase Reference]

568-73-0(CAS DataBase Reference)
Safety DataBack Directory
[Safety Statements ]

24/25
[WGK Germany ]

3
[HS Code ]

29329990
Hazard InformationBack Directory
[Chemical Properties]

Purple to Brown powder
[Uses]

Tanshinone I is an extract from Danshen (Radix Salvia miltiorrhizae) and has been used for the treatment of cerebrovascular diseases such as ischemic stroke.
[Definition]

ChEBI: Tanshinone I is an abietane diterpenoid. It has a role as an anticoronaviral agent.
[Biological Activity]

Phenanthrenequinone constituent of Chinese medicinal herb Danshen (Salvia miltiorrhiza). Modulates or prevents breast cancer metastasis by regulating adhesion molecules. Anti-inflammatory.''TanshinoneI is extensively studied for its anticancer propertiesit was reported to inhibit cancer cell invasionmetastasisand migration and is a potent antitumor agent. It also displays antibacterialneuroprotectivememory-enhancingand cardioprotective activities.
[Cytotoxicity]

IC50 (μg/mL): 2.96 (A549), 2.14 (TOV-21G) (Chang et al. 2013)
IC50 (μg/mL): 10.5 (MIAPaCa-2) (Fronzaet al. 2011)
Spectrum DetailBack Directory
[Spectrum Detail]

Tanshinone I(568-73-0)MS
Tanshinone I(568-73-0)IR1
Tanshinone I(568-73-0)IR2
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