Identification | More | [Name]
6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE | [CAS]
5617-70-9 | [Synonyms]
6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE CYCL-ISOPROPYLIDENE CYCLOPROPANE-1,1-DICARBOXYLATE CYCLOPROPANE-1,1-DICARBOXYLIC ACID CYCL-ISOPROPYLIDENE ESTER CYCLOPROPANE-1,1-DICARBOXYLIC ACID CYCLOISOPROPYLIDENE ESTER 1,1-Cyclopropanedicarboxylic acid cycl-isopropylidene ester~cycl-Isopropylidene 1,1-cyclopropanedicarboxylate CYCLOPROPYL MELDRUM'S ACID Danishefsky's reagent CYCLOPROPANE-1,1-DICARBOXYLIC ACID CYCL-ISOPRYLIDENE ESTER Cyclopropane-1,1-dicarboxylic acid cyclic-isopropylidene ester 1,1-Cyclopropanedicarboxylic acid cyclic isopropylidene ester, 6,6-Dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione cyclic Isopropylidene 1,1-cyclopropanedicarboxylate 2,2-Dimethylspiro[1,3-dioxane-5,1'-cyclopropane]-4,6-dione 3,3-Dimethyl-2,4-dioxaspiro[5.2]octane-1,5-dione 5,7-Dioxa-6,6-dimethylspiro[2.5]octane-4,8-dione Cyclopropane-1,1-dicarboxylic acid isopropylidene ester | [EINECS(EC#)]
227-044-5 | [Molecular Formula]
C8H10O4 | [MDL Number]
MFCD00042796 | [Molecular Weight]
170.16 | [MOL File]
5617-70-9.mol |
Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust . S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
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Hazard Information | Back Directory | [Uses]
6,6-Dimethyl-5,7-dioxaspiro[2.5]octan-4,8-dione is used as a reagent to synthesize Bis-benzimidazoles, compounds that act as inhibitors of Type II Dihydrofolate reductase (an enzyme that is produced by bacteria in response to Trimethoprim [T795615]as a defense mechanism). | [Synthesis Reference(s)]
Organic Syntheses, Coll. Vol. 7, p. 411, 1990 The Journal of Organic Chemistry, 40, p. 2969, 1975 DOI: 10.1021/jo00908a030 |
Spectrum Detail | Back Directory | [Spectrum Detail]
6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE(5617-70-9)MS 6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE(5617-70-9)1HNMR 6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE(5617-70-9)13CNMR 6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE(5617-70-9)IR1 6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE(5617-70-9)IR2
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