Identification | More | [Name]
4-Chlorophenylacetone | [CAS]
5586-88-9 | [Synonyms]
1-(4-CHLOROPHENYL)ACETONE 1-(4-CHLOROPHENYL)PROPAN-2-ONE 4'-CHLOROPHENYLACETONE 4-CHLOROPHENYLACETONE P-CHLORO BENZYL METHYL KETONE (P-CHLOROPHENYL)ACETONE 1-(p-chlorophenyl)acetone 2-Propanone, 1-(4-chlorophenyl)- 2-Propanone,1-(4-chlorophenyl)- 4-Chlorphenylaceton P-CHLORO ENZYL METHYL KETONE 4-CHLOROPHENYLACETONE 98% 1-(4-Chlorophenyl)-2-propanone 4-Chlorophenylmethyl(methyl) ketone | [EINECS(EC#)]
226-986-4 | [Molecular Formula]
C9H9ClO | [MDL Number]
MFCD00045214 | [Molecular Weight]
168.62 | [MOL File]
5586-88-9.mol |
Hazard Information | Back Directory | [Chemical Properties]
clear light yellow liquid | [Uses]
4-Chlorophenylacetone is a phenylacetone derivative used in the preparation of biologically active compounds such as anorectic agents. | [Preparation]
At present, there are three main synthetic routes for 4-chlorophenylacetone. The first is to synthesize 4-chlorophenylacetone with sodium p-chlorobenzenesulfonate and acetone as raw materials, with a yield of about 54%. The second synthesis route is to synthesize 4-chlorophenylacetone with p-chlorobenzenesulfonyl chloride and chloroacetone as raw materials. The third synthesis route is to synthesize 4-chlorophenylacetone from chloroacetone. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 48, p. 2590, 1983 DOI: 10.1021/jo00163a034 | [Health Hazard]
When it contacts with skin and mucous membrane, 4-chlorophenylacetone will cause inflammation, so pay attention to safety when using 4-chlorophenylacetone. This chemical is harmful to environment. It should be prevented from contacting groundwater, waterways or sewage systems. Without government permission, 4-chlorophenylacetone should not be discharged into the surrounding environment. |
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