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ChemicalBook--->CAS DataBase List--->55750-61-3

55750-61-3

55750-61-3 Structure

55750-61-3 Structure
IdentificationBack Directory
[Name]

N-Succinimidyl maleimidoacetate
[CAS]

55750-61-3
[Synonyms]

MaleiMidoacetic
a-Maleimidoacetic acid-NHS
N-SUCCINIMIDYL MALEIMIDOACETATE
N-(α-MaleiMidoacetoxy)succiMide
a-MaleiMidoacetic acid-NHS(AMAS)
AMAS N-Succinimidyl maleimidoacetate
N-(α-Maleimidoacetoxy)succinimide Ester(AMAS)
MALEIMIDOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER
2,5-Dioxopyrrolidin-1-yl 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)
1-[2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-1H-pyrrole-2,5-dione
1H-Pyrrole-2,5-dione, 1-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-
2,5-Dioxopyrrolidin-1-yl 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetate
[Molecular Formula]

C10H8N2O6
[MDL Number]

MFCD00133523
[MOL File]

55750-61-3.mol
[Molecular Weight]

252.18
Chemical PropertiesBack Directory
[Appearance]

White Crystalline Solid
[Melting point ]

174-175°C
[Boiling point ]

430.1±47.0 °C(Predicted)
[density ]

1.63±0.1 g/cm3(Predicted)
[storage temp. ]

−20°C
[solubility ]

Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated)
[form ]

Solid
[pka]

-2.69±0.20(Predicted)
[color ]

White to Off-White
[InChI]

InChI=1S/C10H8N2O6/c13-6-1-2-7(14)11(6)5-10(17)18-12-8(15)3-4-9(12)16/h1-2H,3-5H2
[InChIKey]

TYKASZBHFXBROF-UHFFFAOYSA-N
[SMILES]

N1(CC(ON2C(=O)CCC2=O)=O)C(=O)C=CC1=O
[CAS DataBase Reference]

55750-61-3
Hazard InformationBack Directory
[Chemical Properties]

White Crystalline Solid
[Uses]

A hetero-bifunctional cross-linking reagent for the preparation of protein-protein or protein-hapten conjugates
[Uses]

Maleimidoacetic acid N-hydroxysuccinimide ester is a crosslinking reagent that contains NHS ester- and maleimide-reactive groups at the opposite ends of a 4.4 ? spacer arm. This configuration allows for sequential, two-stage conjugation with amine and sulfhydryl functional groups in the preparation of protein-hapten or protein-protein conjugates.
[reaction suitability]

reagent type: linker
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36
[WGK Germany ]

3
[HS Code ]

29280000
Spectrum DetailBack Directory
[Spectrum Detail]

N-Succinimidyl maleimidoacetate(55750-61-3)1HNMR
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