| Identification | Back Directory | [Name]
N-Succinimidyl maleimidoacetate | [CAS]
55750-61-3 | [Synonyms]
MaleiMidoacetic
a-Maleimidoacetic acid-NHS
N-SUCCINIMIDYL MALEIMIDOACETATE
N-(α-MaleiMidoacetoxy)succiMide
a-MaleiMidoacetic acid-NHS(AMAS)
AMAS N-Succinimidyl maleimidoacetate
N-(α-Maleimidoacetoxy)succinimide Ester(AMAS)
MALEIMIDOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER
2,5-Dioxopyrrolidin-1-yl 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)
1-[2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-1H-pyrrole-2,5-dione
1H-Pyrrole-2,5-dione, 1-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-
2,5-Dioxopyrrolidin-1-yl 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetate | [Molecular Formula]
C10H8N2O6 | [MDL Number]
MFCD00133523 | [MOL File]
55750-61-3.mol | [Molecular Weight]
252.18 |
| Chemical Properties | Back Directory | [Appearance]
White Crystalline Solid | [Melting point ]
174-175°C | [Boiling point ]
430.1±47.0 °C(Predicted) | [density ]
1.63±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated) | [form ]
Solid | [pka]
-2.69±0.20(Predicted) | [color ]
White to Off-White | [InChI]
InChI=1S/C10H8N2O6/c13-6-1-2-7(14)11(6)5-10(17)18-12-8(15)3-4-9(12)16/h1-2H,3-5H2 | [InChIKey]
TYKASZBHFXBROF-UHFFFAOYSA-N | [SMILES]
N1(CC(ON2C(=O)CCC2=O)=O)C(=O)C=CC1=O | [CAS DataBase Reference]
55750-61-3 |
| Hazard Information | Back Directory | [Chemical Properties]
White Crystalline Solid | [Uses]
A hetero-bifunctional cross-linking reagent for the preparation of protein-protein or protein-hapten conjugates | [Uses]
Maleimidoacetic acid N-hydroxysuccinimide ester is a crosslinking reagent that contains NHS ester- and maleimide-reactive groups at the opposite ends of a 4.4 ? spacer arm. This configuration allows for sequential, two-stage conjugation with amine and sulfhydryl functional groups in the preparation of protein-hapten or protein-protein conjugates. |
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