| Identification | More | [Name]
p-Acetylamino benzoic acid | [CAS]
556-08-1 | [Synonyms]
4-ACETAMIDOBENZOIC ACID
4-(ACETYLAMINO)BENZENECARBOXYLIC ACID
4-ACETYLAMINOBENZOIC ACID
ACETYLATED PABA
N-(4-Carboxyphenyl)acetic acid amide
N-ACETYL-1-AMINO-4-CARBOXYBENZENE
N-ACETYL-4-CARBOXYANILINE
N-ACETYL-PABA
n-acetyl-p-aminobenzoic acid
PAABA
P-ACETAMIDOBENZOIC ACID
P-ACETAMIDOPHENYLCARBOXYLIC ACID
P-ACETAMINOBENZOIC ACID
P-ACETAMINOPHENYLCARBOXYLIC ACID
P-ACETYLAMIDOBENZOIC ACID
P-ACETYLAMINO BENZOIC ACID
P-ACETYLAMINOPHENYLCARBOXYLIC ACID
RARECHEM AL BO 0055
4-(acetylamino)-benzoicaci
4'-Carboxyacetanilide | [EINECS(EC#)]
209-114-7 | [Molecular Formula]
C9H9NO3 | [MDL Number]
MFCD00002534 | [Molecular Weight]
179.17 | [MOL File]
556-08-1.mol |
| Chemical Properties | Back Directory | [Appearance]
white or off-white powder or crystals | [Melting point ]
259-262 °C (dec.)(lit.)
| [Boiling point ]
311.69°C (rough estimate) | [density ]
1.2822 (rough estimate) | [refractive index ]
1.5600 (estimate) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Powder | [pka]
pK1: 4.28 (25°C) | [color ]
Off-white to slightly beige | [Stability:]
Stable. Combustible. Incompatible with strong oxidizing agents. | [Water Solubility ]
<0.1 g/100 mL at 21 ºC | [BRN ]
390602 | [CAS DataBase Reference]
556-08-1(CAS DataBase Reference) | [NIST Chemistry Reference]
N-(4-Carboxyphenyl)acetic acid amide(556-08-1) | [EPA Substance Registry System]
556-08-1(EPA Substance) |
| Safety Data | Back Directory | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [TSCA ]
Yes | [HS Code ]
29242995 |
| Hazard Information | Back Directory | [General Description]
Needles or off-white powder. | [Reactivity Profile]
Simultaneously an amide and a carboxylic acid. | [Air & Water Reactions]
Water insoluble. | [Fire Hazard]
Flash point data for this chemical are not available; however, P-ACETAMIDOBENZOIC ACID is probably combustible. | [Chemical Properties]
white or off-white powder or crystals | [Originator]
4-Acetamidobenzoic acid ,ARIAC | [Uses]
Acedoben is the acetylated derivative of p-aminobenzoic acid (PABA). Acedoben is a metabolite of the anesthetic Benzocaine (B202970). | [Uses]
immune stimulant (component) | [Definition]
ChEBI: A amidobenzoic acid that consists of benzoic acid bearing an acetamido substituent at position 4. | [Manufacturing Process]
Into a 2 L, 3-necked flask set in a tub and equipped with a stirrer, an air
condenser (drying tube), thermometer, was placed 860 ml of water, 43.0 g of
MgSO4 and 43.0 g of sodium acetate and heated on water bath. Into heated
solution to 70°C stirring 43.0 g of N-p-tolylacetamide were added. Then 136.0
g of KMnO4 by small portions were added at 75°-80°C. The reaction mixture
allow to stand for 6 h and stirring was continue till the solution became
colorless. Hot solution was filtered and filtrate treated hydrochloric acid to
slightly acidic pH. After that 44.0 g (85%) of p-acetoaminobenzoic acid was
obtained as white precipitate, melting point 250°C. | [Therapeutic Function]
Antiviral | [reaction suitability]
reaction type: solution phase peptide synthesis |
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