| Identification | More | [Name]
4-Chloro-7-azaindole | [CAS]
55052-28-3 | [Synonyms]
1H-PYRROLO[2,3-B]PYRIDINE, 4-CHLORO-
4-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE
4-CHLORO-7-AZAINDOLE
IFLAB-BB F2108-0145
4-Chloro-1H-pyrrolo[2,3-b]pyridin
4-Chloro-1H-pyrrolo[2,3-β]pyridine | [EINECS(EC#)]
626-806-8 | [Molecular Formula]
C7H5ClN2 | [MDL Number]
MFCD08272232 | [Molecular Weight]
152.58 | [MOL File]
55052-28-3.mol |
| Chemical Properties | Back Directory | [Melting point ]
176-181 °C | [density ]
1.425±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
solid | [pka]
12.98±0.40(Predicted) | [color ]
Light yellow to brown | [Water Solubility ]
Slightly soluble in water. | [Usage]
A useful intermediate for drug discovery research | [Detection Methods]
HPLC | [InChI]
InChI=1S/C7H5ClN2/c8-6-2-4-10-7-5(6)1-3-9-7/h1-4H,(H,9,10) | [InChIKey]
HNTZVGMWXCFCTA-UHFFFAOYSA-N | [SMILES]
C12NC=CC1=C(Cl)C=CN=2 | [CAS DataBase Reference]
55052-28-3(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R22:Harmful if swallowed.
R37/38:Irritating to respiratory system and skin .
R41:Risk of serious damage to eyes. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S39:Wear eye/face protection . | [RIDADR ]
UN 2811 6.1/PG 3 | [WGK Germany ]
3 | [HazardClass ]
6.1 | [HazardClass ]
IRRITANT | [PackingGroup ]
Ⅲ | [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Description]
4-Chloro-7-azaindole belongs to the class of azaindole compounds, which has anticancer, antibacterial, antiviral and other biological activities. 4-Chloro-7-azaindole is mainly used as an organic intermediate in the preparation of 7-azaindole derivatives, GDC-0575, and Janus kinase inhibitors. | [Chemical Properties]
White to brown solid | [Uses]
4-Chloro-7-azaindole can be used as a useful intermediate for drug discovery research.
| [Synthesis Reference(s)]
The Journal of Organic Chemistry, 71, p. 4021, 2006 DOI: 10.1021/jo0602571 |
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