| Identification | More | [Name]
5-Amino-4,6-dichloropyrimidine | [CAS]
5413-85-4 | [Synonyms]
4,6-DICHLORO-5-PYRIMIDINAMINE
4,6-DICHLOROPYRIMIDIN-5-AMINE
4,6-DICHLOROPYRIMIDIN-5-YLAMINE
5-AMINO-4,6-DICHLOROPYFIMIDINE
5-AMINO-4,6-DICHLOROPYRIMIDINE
5-PYRIMIDINAMINE, 4,6-DICHLORO-
AKOS 91433
TIMTEC-BB SBB003920
4,6-Dichloro-5-aminopyrimidine
4,6-dichloro-5-pyrimidinamin
Pyrimidine, 5-amino-4,6-dichloro-
5-AMINO-4,6-DICHLORPYRIMIDIN 97%
5-Amino-4,6-dichloro
5-amine-4,6-dichloropyrimidine
5-Amino-4,6-dichloropyrimidine, 98+% | [EINECS(EC#)]
226-503-7 | [Molecular Formula]
C4H3Cl2N3 | [MDL Number]
MFCD00006108 | [Molecular Weight]
163.99 | [MOL File]
5413-85-4.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [F ]
10-21 | [TSCA ]
Yes | [HS Code ]
29335900 |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Ethyl acetate-->Nitric acid-->Phosphorus oxychloride-->Hexane-->Trifluoroacetic acid-->Stannous chloride dihydrate-->N,N-Diisopropylethylamine-->4,6-Dihydroxypyrimidine | [Preparation Products]
4,5-Diaminopyrimidine-->5-Pyrimidinamine, 1,4,5,6-tetrahydro--->2-(5-AMINO-6-CHLORO-PYRIMIDIN-4-YLAMINO)-ETHANOL-->6-CHLORO-N4-(4-CHLOROPHENYL)-4,5-PYRIMIDINEDIAMINE-->4-(5-AMINO-6-CHLORO-4-PYRIMIDINYL)-1-PIPERAZINECARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER-->6-chloro-N4-ethylpyrimidine-4,5-diamine-->(R)-1-((5-aMino-6-chloropyriMidin-4-yl)aMino)propan-2-ol-->4-CHLORO-6-HYDRAZINO-PYRIMIDIN-5-YLAMINE |
| Hazard Information | Back Directory | [Chemical Properties]
Yellowish-brown crystals or powder | [Uses]
5-Amino-4,6-dichloropyrimidine was used in the synthesis of:
- oxepane ring containing monocyclic, conformationally restricted bicyclic and spirocyclic nucleosides
- conformationally locked bicyclo[2.2.1]heptane/oxa-bicyclo[3.2.1]octane nucleosides
- N(7)-substituted purines
- chiral derivatives of (+)-erythro-9-(2-hydroxy-3-nonyl)adenine
- 9-alkyl-6-substituted-purine analogs, potent anticonvulsant agents
- pyrimido-oxazepines in a three-step process with microwave heating at 150°C
| [Uses]
An intermediate in the production of many biological inhibitors. |
|
|