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ChemicalBook--->CAS DataBase List--->53413-67-5

53413-67-5

53413-67-5 Structure

53413-67-5 Structure
IdentificationBack Directory
[Name]

4,5-DIMETHOXY-2-NITROBENZYL BROMIDE
[CAS]

53413-67-5
[Synonyms]

6-NITROVERATRYL BROMIDE
-4,5-dimethoxy-2-nitrobenzene
-4,5-dimethoxy-2-nitrobenzene
4,5-dimenoxy-2-nitrobenzyl bromide
3,4-Dimethoxy-6-nitrobenzyl bromide
4,5-DIMETHOXY-2-NITROBENZYL BROMIDE
4,5-Dimethoxy-2-nitrobenzyl bromide 95%
4,5-Dimethoxy-2-nitro-1-bromomethylbenzene
1-(bromomethyl)-2-nitro-4,5-dimethoxybenzene
1-(Bromomethyl)-4,5-dimethoxy-2-nitrobenzene
Benzene, 1-(bromomethyl)-4,5-dimethoxy-2-nitro-
JR-13611, 1-(Bromomethyl)-4,5-dimethoxy-2-nitrobenzene, 97%
[Molecular Formula]

C9H10BrNO4
[MDL Number]

MFCD00192064
[MOL File]

53413-67-5.mol
[Molecular Weight]

276.08
Chemical PropertiesBack Directory
[Melting point ]

131-133 °C(lit.)
[Boiling point ]

372.3±37.0 °C(Predicted)
[density ]

1.544
[storage temp. ]

under inert gas (nitrogen or Argon) at 2-8°C
[form ]

Crystalline Powder or Needles
[color ]

Yellow to brown
[Sensitive ]

Lachrymatory
Safety DataBack Directory
[Hazard Codes ]

C
[Risk Statements ]

34
[Safety Statements ]

22-26-27-36/37/39-45
[RIDADR ]

UN 3261 8/PG 2
[WGK Germany ]

3
[HazardClass ]

8
[PackingGroup ]

III
[HS Code ]

29093090
Hazard InformationBack Directory
[Uses]

1-(Bromomethyl)-4,5-dimethoxy-2-nitrobenzene is a useful research chemical.
[Uses]

4,5-Dimethoxy-2-nitrobenzyl bromide (DMNB bromide, 6-nitroveratryl bromide) is suitable reagent used in the synthesis of N-(4,5-dimethoxy-2-nitrobenzyl)vanillylamine which forms caged vanilloid. It may be used in the synthesis of the following:
  • 4-(4′,5′-dimethoxy-2-nitrobenzyloxy)benzaldehyde, a DMNB-caged aldehyde
  • N-[4-[(4,5-dimethoxy-2-nitrobenzyl)oxy]-3-methoxybenzyl]acetamide
  • caged derivative of pyridostatin ([C]-PDS)
  • photosensitive polyimide (PI-DMNB)
  • caged β-ecdysone
  • 4-tert-butyldimethylsilyloxy-1-(2-deoxy-3,5-di-O-toluoyl-β-D-ribofuranosyl)-2-(6-nitroveratrylthio)-1H-benzimidazole, an intermediate in synthesis of phosphoramidite bearing 4-hydroxy-2-mercaptobenzimidazole (SBNV) nucleobase
  • alkylation of dihydrofluorescein
  • 4-(4′,5′-Dimethoxy-2′-nitrobenzyloxy)benzaldehyde
[General Description]

4,5-Dimethoxy-2-nitrobenzyl bromide (DMNBB, 1-(Bromomethyl)-4,5-dimethoxy-2-nitrobenzene) is a 4,5-dimethoxy-2-nitrobenzyl derivative. 4,5-Dimethoxy-2-nitrobenzyl (DMNB) group of DMNBB is used as a photolabile protecting group in caging technology to develop pro-drugs. Synthesis of 1-(bromomethyl)-4,5-dimethoxy-2-nitrobenzene by using 6-nitroveratraldehyde as starting reagent has been reported.
Spectrum DetailBack Directory
[Spectrum Detail]

4,5-DIMETHOXY-2-NITROBENZYL BROMIDE(53413-67-5)FT-IR
4,5-DIMETHOXY-2-NITROBENZYL BROMIDE(53413-67-5)IR
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