| Identification | Back Directory | [Name]
3-N-OXALYL-L-2,3-DIAMINOPROPANOICACID | [CAS]
5302-45-4 | [Synonyms]
ODAP
BOAA
β-ODAP
10-25Mg
β-L-ODAP
Dencichin
L-Dencichin
beta-ODAP >=98% (HPLC)
β-N-Oxalylamino-L-alanine
BETA-N-OXALAMINO-L-ALANINE
BETA-N-OXYALYLAMINE-L-ALANINE
DENCICHINE; L-DENCICHIN; ODAP
N3-oxalyl-L-2,3-diaminopropionicaci
3-[(Carboxycarbonyl)amino]-L-alanine
3-N-OXALYL-L-2,3-DIAMINOPROPANOICACID
L-Alanine, 3-[(carboxycarbonyl)amino]-
N(3)-oxalyl-L-2,3-diaminopropionic acid
BETA-N-OXALYL-ALPHA,BETA-DIAMINOPROPIONICACID
(S)-2-AMino-3-(carboxyforMaMido)propanoic acid
(S)-2-Amino-3-[(1,2-dioxo-2-hydroxyethyl)amino]propionic acid | [Molecular Formula]
C5H8N2O5 | [MDL Number]
MFCD00055228 | [MOL File]
5302-45-4.mol | [Molecular Weight]
176.13 |
| Chemical Properties | Back Directory | [density ]
1.596±0.06 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [solubility ]
0.1 M HCl: soluble2mg/mL, clear (warmed) | [form ]
powder | [pka]
1.99±0.10(Predicted) | [color ]
white to beige | [optical activity]
[α]/D -17 to -23°, c = 0.5 (Solvent: 4N HCl) |
| Hazard Information | Back Directory | [Definition]
ChEBI: An Nbeta-acyl-L-2,3-diaminopropionic acid in which the acyl group is oxalyl. | [Biological Activity]
β-ODAP is a potent inhibitor of HIF-prolyl hydroxylase-2 (PHD-2) th at induces HIF dependent HRE (hypoxia response element) in normoxic conditions. β-ODAP is an analog of glutamic acid present in Lathyrus sativus (grass pea) th at activates AMPA receptors. β-ODAP causes neurolathyrism upon prolonged consumption of L. sativus seeds.''β-ODAP is considered more neurotoxic than α-ODAPthus during food processingits conversion to α isomer is essential. β-ODAP exhibits its neurotoxicity via the activation of metabotropic glutamatergic receptor. |
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