| Identification | More | [Name]
4-Hydroxy-3,5-dimethoxycinnamic acid | [CAS]
530-59-6 | [Synonyms]
3,5-DIMETHOXY-4-HYDROXYCINNAMIC ACID
3,5-DIMETHOXY-4-HYDROXYCINNAMIC ACID, TRANS
3,5-DIMETHOXY-4-HYDROXY-TRANS-CINNAMIC ACID
4-HYDROXY-3,5-DIMETHOXYCINNAMIC ACID
LABOTEST-BB LT00233169
RARECHEM BK HW 0169
SINAPIC ACID
SINAPINIC ACID
(2E)-3-(4-Hydroxy-3,5-dimethoxyphenyl)-2-propenoic acid
2-Propenoic acid, 3-(4-hydroxy-3,5-dimethoxyphenyl)-
3,5-dimethoxy-4-hydroxycinnamicacid(sinapinicacid)
3,5-dimethoxy-4-hydroxycinnamicacid,predominantlytransisomer
trans-3,5-Dimethoxy-4-hydroxycinnamic acid
SINAPINIC ACID, USE TESTED FOR MALDI-TOF MASS SPEC
3,5-DIMETHOXY-4-HYDROXYCINNAMIC ACID, 98 %, PREDOMINANTLY TRANS
SINAPIC ACID, PGE. WITH 10 X 10 MG
SINAPIC ACID, MATRIX SUBSTANCE FOR MALDI MS
Sinapinicacid=Sinapicacid
3,5-Dimethoxy-4-hydroxycinnamic acid, 4-Hydroxy-3,5-dimethoxy-cinnamic acid, Sinapinic acid
3,5-Dimethoxy-4-hydroxycinnamic acid, 4-Hydroxy-3,5-dimethoxycinnamic acid, Sinapic acid | [EINECS(EC#)]
208-487-3 | [Molecular Formula]
C11H12O5 | [MDL Number]
MFCD00004401 | [Molecular Weight]
224.21 | [MOL File]
530-59-6.mol |
| Chemical Properties | Back Directory | [Appearance]
yellow-brown crystalline powder | [Melting point ]
~202 °C | [Boiling point ]
285.61°C (rough estimate) | [density ]
1.1478 (rough estimate) | [refractive index ]
1.4720 (estimate) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
H2O: slightly soluble
| [form ]
powder
| [pka]
4.53±0.10(Predicted) | [color ]
white
| [Odor]
at 100.00?%. odorless | [Stability:]
Stable. Incompatible with strong oxidizing agents, strong bases. Combustible. | [Water Solubility ]
insoluble | [BRN ]
2130006 | [LogP]
0.997 (est) | [CAS DataBase Reference]
530-59-6(CAS DataBase Reference) | [NIST Chemistry Reference]
Cinnamic acid, 4-hydroxy-3,5-dimethoxy-(530-59-6) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HS Code ]
29189900 |
| Hazard Information | Back Directory | [Chemical Properties]
yellow-brown crystalline powder | [Uses]
4-Hydroxy-3,5-dimethoxycinnamic acid is a commonly used matrix in MALDI mass spectrometry. It is a useful matrix for a wide variety of peptides and proteins. It serves well as a matrix for MALDI due to its ability to absorb laser radiation and to also donate protons (H+) to the analyte of interest. | [Definition]
ChEBI: A monohydroxycinnamic acid that is cinnamic acid in which the phenyl hydrogens at positions 3, 4, and 5 are replaced by methoxy, hydroxy, and methoxy groups, respectively. | [General Description]
Sinapic acid is an hydroxycinnamic acid derivative that occurs naturally in Brassicaceae species. | [Biochem/physiol Actions]
On removal of amino group from phenylalanine, catalysing with enzyme phenylalanine ammonia-lyase forms cinnamic acid. The precursor of hydroxycinnamates is produced after hydroxylation of benzene ring. One of the precursors produced is sinapic acid. Sinapic acid exhibits antimicrobial, antioxidant, anticancer, anti-inflammatory, and anti-anxiety activity. Sinapine (sinapoyl choline) has been acknowledged as an acetylcholinesterase inhibitor, making it therapeutically applicable in treatment of various diseases. 4-Vinylsyringol (a decarboxylation product of sinapic acid) is a potent antimutagenic and antioxidative agent, involved in suppressing the induction of inflammatory cytokines and carcinogenesis. Owing to their anti-oxidative activity, these compounds have been considered to be potentially employed in the pharmaceutical industry, cosmetics and food processing. | [Purification Methods]
Crystallise it from water. [Beilstein 10 H 508, 10 IV 2104.] |
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