| Identification | More | [Name]
5-Aminoindole | [CAS]
5192-03-0 | [Synonyms]
1H-INDOL-5-AMINE
1H-INDOL-5-YLAMINE
5-AMINO-1H-INDOLE
5-AMINOINDOLE
5-INDOLAMINE
5-INDOLYLAMINE
AKOS 91148
INDOLE-5-AMINE
TIMTEC-BB SBB004219
Indole, 5-amino-
indol-5-ylamine
5-Aminoindole
H-Indol-5-amine
H-Indol-5-amine
indolin-5-amine
5-AMINOINDOLE 98+%
1H-Indole-5-amine | [EINECS(EC#)]
225-977-2 | [Molecular Formula]
C8H8N2 | [MDL Number]
MFCD00005679 | [Molecular Weight]
132.16 | [MOL File]
5192-03-0.mol |
| Chemical Properties | Back Directory | [Appearance]
Grey Crystals | [Melting point ]
131-133 °C (dec.) (lit.) | [Boiling point ]
190 °C / 6mmHg | [density ]
1.1083 (rough estimate) | [refractive index ]
1.6013 (estimate) | [storage temp. ]
0-6°C | [solubility ]
DMSO, Methanol | [form ]
Crystalline Powder | [pka]
17.39±0.30(Predicted) | [color ]
Off-white to gray-brown | [Water Solubility ]
insoluble | [Sensitive ]
Air & Light Sensitive | [Detection Methods]
HPLC | [BRN ]
112348 | [InChIKey]
ZCBIFHNDZBSCEP-UHFFFAOYSA-N | [CAS DataBase Reference]
5192-03-0(CAS DataBase Reference) | [NIST Chemistry Reference]
5-Aminoindole(5192-03-0) | [Storage Precautions]
Store under nitrogen | [EPA Substance Registry System]
5192-03-0(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
R68:Possible risk of irreversible effects. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37:Wear suitable protective clothing and gloves . | [WGK Germany ]
3
| [F ]
10 | [Hazard Note ]
Irritant | [TSCA ]
Yes | [HazardClass ]
AIR SENSITIVE, IRRITANT-HARMFUL, KEEP COLD | [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Chemical Properties]
Grey Crystals | [Uses]
Reactant for preparation of:
- Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP
- Cytotoxic and antimitotic agents
- Insulin-like growth factor 1 receptor inhibitors
- Antitumoral agents
- Factor Xa inhibitor
- Potential antivascular agents
- Gli1-mediated transcription in the Hedgehog pathway
- Inhibitors of receptor tyrosine kinase with antiangiogenic effects
- PKCθ inhibitors
- HIV protease inhibitors
| [Definition]
ChEBI: An indolamine carrying an amino group at position 5. |
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