| Identification | Back Directory | [Name]
Mal-PEG6-Acid | [CAS]
518044-42-3 | [Synonyms]
Mal-PEG7-acid
Mal-PEG6-Acid
Mal-PEG6-CH2CH2COOH
Maleimide-PEG6-CH2CH2COOH
21-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-4,7,10,13,16,19-hexaoxaheneicosanoic acid
4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)- | [Molecular Formula]
C19H31NO10 | [MDL Number]
MFCD22056307 | [MOL File]
518044-42-3.mol | [Molecular Weight]
433.45 |
| Chemical Properties | Back Directory | [Boiling point ]
578.2±50.0 °C(Predicted) | [density ]
1.234±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Water, DMSO, DCM, DMF | [form ]
Liquid | [pka]
4.28±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
Mal-PEG6-acid is a PEG linker containing a maleimide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | [Uses]
Mal-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. | [IC 50]
PEGs |
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