| Identification | Back Directory | [Name]
TBTA | [CAS]
510758-28-8 | [Synonyms]
TBTA ISO 9001：2015 REACH
Tris-(benzyltriazolylmethyl)amine
Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)Methyl]aMine 97%
N,N,N-Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine
Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine
Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine, 97% TBTA
1-(1-Benzyltriazol-4-yl)-N,N-bis[(1-benzyltriazol-4-yl)methyl]methanamine
1H-1,2,3-Triazole-4-methanamine, 1-(phenylmethyl)-N,N-bis[[1-(phenylmethyl)-1H-1,2,3-triazol-4-yl]methyl]- | [EINECS(EC#)]
693-028-3 | [Molecular Formula]
C30H30N10 | [MDL Number]
MFCD09265124 | [MOL File]
510758-28-8.mol | [Molecular Weight]
530.626 |
| Chemical Properties | Back Directory | [Melting point ]
132-143℃ | [Boiling point ]
762.4±70.0 °C(Predicted) | [density ]
1.27±0.1 g/cm3(Predicted) | [storage temp. ]
?20°C | [solubility ]
Soluble in DMSO, DMF. | [form ]
Solid | [pka]
2.44±0.50(Predicted) | [color ]
White | [Stability:]
store cold | [InChIKey]
WKGZJBVXZWCZQC-UHFFFAOYSA-N | [SMILES]
N1(CC2=CC=CC=C2)C=C(CN(CC2=CN(CC3=CC=CC=C3)N=N2)CC2=CN(CC3=CC=CC=C3)N=N2)N=N1 |
| Hazard Information | Back Directory | [Description]
TBTA was introduced shortly after the copper-catalyzed azide-alkyne cycloaddition reaction was discovered to mitigate thermodynamic instability of Cu(I) in aerobic media. TBTA is a water-insoluble ligand and must be first dissolved in DMSO or DMF.
J Am Chem Soc., 143 (18), 6787-6791.
T. R. Chan, R. Hilgraf, K. B. Sharpless, V. V. Fokin, Org. Lett. 2004, 6, 2853. | [Uses]
Tris-(benzyltriazolylmethyl)amine is a useful reagent for copper (I) catalyzed azide-alkyne cycloadditions.?It can also be used for postsynthetic labelling of alkyne-modified DNA. | [reaction suitability]
reagent type: ligand
reaction type: click chemistry | [storage]
Store at -20°C |
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