| Identification | More | [Name]
N,N-Dimethylpiperidin-4-amine | [CAS]
50533-97-6 | [Synonyms]
4-DIMETHYLAMINO-PIPERIDINE
4-(N,N-DIMETHYLAMINO)PIPERIDINE
AKOS BB-9178
CHEMBRDG-BB 4018153
DIMETHYL-PIPERIDIN-4-YL-AMINE
N,N-DIMETHYLPIPERIDIN-4-AMINE
4-(Dimethylamino)piperidine,98%
4-DIMETHYLAMINO-PIPERIDINE 98%
N,N''-DIMETHYLAMINOPIPERIDINE
N,N-Dimethyl-4-piperidinamine
N,N-Dimethylpiperidine-4-amine | [EINECS(EC#)]
256-617-2 | [Molecular Formula]
C7H16N2 | [MDL Number]
MFCD00023144 | [Molecular Weight]
128.22 | [MOL File]
50533-97-6.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R10:Flammable.
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
2734 | [Hazard Note ]
Irritant | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
2933399990 |
| Hazard Information | Back Directory | [Uses]
4-(Dimethylamino)piperidine is having molecular features associated with polyamine modulation of N-methyl-D-aspartate receptors. It is utilized as a mechanism for reducing the effects of alcohol dependence. | [Synthesis]
1-(tert-Butoxycarbonyl)-4-piperidone (998 mg, 4.75 mmol) in methanol (15 mL) was treated with dimethylamine hydrochloride (800 mg, 9.8 mmol) and sodium cyanoborohydride (270 mg, 4.3 mmol) at rt. After 4 days, concentrated HCl (10 mL) was added and volume of the reaction was reduced in vacuo. The resulting residue was dissolved in H2O (30 mL) and treated with a 2M NaOH solution to achieve a pH of 10. The aqueous solution was extracted with methylene chloride (3×20 mL) and the combined organics were dried over Na2SO4 and removed in vacuo. The resulting amine 106 (169 mg). | [storage]
Incompatible with air, water, oxidizing agents and heat. |
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