| Identification | More | [Name]
3-FLUOROBENZHYDRAZIDE | [CAS]
499-55-8 | [Synonyms]
BUTTPARK 35\03-72
3-FLUOROBENZHYDRAZIDE
3-FLUOROBENZOHYDRAZIDE
3-Fluorobenzhydrazide98%
3-Fluorobenzhydrazide 98%
3-FLUOROBENZOIC HYDRAZIDE
3-Fluorobenzoic hydrazide 97%
3-FLUOROBENZOIC ACID HYDRAZIDE
Benzoic acid, 3-fluoro-, hydrazide | [Molecular Formula]
C7H7FN2O | [MDL Number]
MFCD00060561 | [Molecular Weight]
154.14 | [MOL File]
499-55-8.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S36:Wear suitable protective clothing . | [WGK Germany ]
3 | [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT |
| Hazard Information | Back Directory | [Uses]
3-FLUOROBENZHYDRAZIDE can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process. | [Synthesis]
Hydrazides (30-58) were synthesized by one pot conventionalmethod24 Benzoic acid or its derivative (10 mmol) was dissolvedin ethanol (20 mL). Sulfuric acid (3 N, 2 mL) was added and thereaction contents were refluxed for six hours. The reaction wasmonitored with TLC. After the completion of the reaction, the reactionmixture was neutralized by adding solid NaHCO3, and filteredto remove excess of NaHCO3. In the neutralized reaction mixture which contains ethyl ester, hydrazine monohydrate (1.5 mL,3 mmol) was added and refluxed for 3-6 h to complete the reaction.Ethanol and unreacted hydrazine were removed by distillationupto 1/3 volume. The reaction contents were cooled, filteredand recrystallized from methanol to obtain the desired hydrazidecrystals (see Supporting information). |
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