| Identification | Back Directory | [Name]
SULINDAC SULFIDE | [CAS]
49627-27-2 | [Synonyms]
Einecs 256-403-9
SULINDAC SULPHIDE
(Z)-Sulindac sulfide
cis-Sulindac sulfide
Sulindac EP Impurity C (Sulindac Sulfide)
Sulindac Impurity 3（Sulindac EP Impurity C）
(Z)-5-FLUORO-2-METHYL-1-[P-(METHYLTHIO)BENZYLIDENE]INDENE-3-ACETIC ACID
(Z)-5-FLUORO-2-METHYL-1-(4-METHYLTHIOBENZYLIDENE)-1H-INDEN-3-YLACETIC ACID
5-Fluoro-2-methyl-1-[(Z)-[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acid
(Z)-5-fluoro-2-methyl-1-[[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acid
1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylthio)phenyl)methylene)-, (Z)-
1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-[[4-(methylthio)phenyl]methylene]-, (1Z)- | [EINECS(EC#)]
256-403-9 | [Molecular Formula]
C20H17FO2S | [MDL Number]
MFCD00869764 | [MOL File]
49627-27-2.mol | [Molecular Weight]
340.41 |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow Solid | [Uses]
An active metabolite of Sulindac. Inhibits cyclooxygenase, but induces apoptosis by a cyclooxygenase-independent mechanism. Inhibition of Ras activation of Ref-1. Impairs nucleotide exchange on Ras
by CDC25 and accelerates Ras hydrolysis of GTP by p120GAP. | [Definition]
ChEBI: An aryl sulfide that is a metabolite of sulindac. A non-steroidal anti-inflammatory drug, which also has anticancer activity. |
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