| Identification | More | [Name]
N-BENZOYLADENOSINE | [CAS]
4546-55-8 | [Synonyms]
Bz-rA
N6-Bz-rA
N6-Bz-Ar
N4-Benzoyl
N-BENZOYLADENOSINE
N6-BENZOYLADENOSINE
Adenosine, N-benzoyl-
N6-BENZOYL-D-ADENOSINE
N(sup 6)benzoyladenosine
N6-Benzoyladenosine Hydrate
N-BENZOYLADENOSINE USP/EP/BP
N6-Benzoyladenosine Hydrate>
N6-Benzoyladenosine
N6-Benzoyladenosine≥ 99.9% (HPLC)
Benzamide, N-(9-β-D-ribofuranosyl-9H-purin-6-yl)-(8CI)
N-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]benzamide | [EINECS(EC#)]
610-251-3 | [Molecular Formula]
C17H17N5O5 | [MDL Number]
MFCD00056988 | [Molecular Weight]
371.35 | [MOL File]
4546-55-8.mol |
| Chemical Properties | Back Directory | [Melting point ]
141-145 °C(lit.)
| [alpha ]
-49o (C=1% IN DMSO) | [density ]
1.70 | [refractive index ]
-48 ° (C=1, DMSO) | [storage temp. ]
Store at 0°C | [form ]
powder to crystal | [pka]
7.87±0.43(Predicted) | [color ]
White to Almost white | [optical activity]
[α]20/D -49°, c = 1% in DMSO | [BRN ]
632501 | [InChIKey]
NZDWTKFDAUOODA-CNEMSGBDSA-N | [SMILES]
OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)NC(=O)C3=CC=CC=C3)N=C2)[C@H](O)[C@@H]1O | [CAS DataBase Reference]
4546-55-8(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
Solid | [Uses]
N6-Benzoyladenosine is an anti tumor agent. | [Synthesis]
In the prior art, the method for preparing N-Benzoyladenosine generally adopts trimethylchlorosilane protection to obtain trimethyl protected adenosine, then benzoyl chloride is added for benzoylation. Finally, the protection is removed under the protection of ammonia water, then the benzoyl chloride is concentrated, the solvent is evaporated to dryness, and water is added for crystallization to afford N-Benzoyladenosine.
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