| Identification | More | [Name]
O-(TERT-BUTYLDIMETHYLSILYL)HYDROXYLAMINE | [CAS]
41879-39-4 | [Synonyms]
AKOS 91557
AMINOXY-TERT-BUTYLDIMETHYLSILANE
O-(T-BUTYLDIMETHYLSILYL)HYDROXYLAMINE
O-(TERT-BUTYLDIMETHYLSILYL)HYDROXYLAMINE
O-(tert-Butyldiemthylsilyl)hydroxylamine
OtertButyldiemthylsilylhydroxylamine
o-(tert-butyldimethylsilyl)hydroxylamine, 95
tert-Butyldimethylsilyloxyamine. | [Molecular Formula]
C6H17NOSi | [MDL Number]
MFCD00054944 | [Molecular Weight]
147.29 | [MOL File]
41879-39-4.mol |
| Chemical Properties | Back Directory | [Melting point ]
62-65 °C (lit.) | [Boiling point ]
87-90 °C/40 mmHg (lit.) | [density ]
0.849±0.06 g/cm3(Predicted) | [Fp ]
54°C | [storage temp. ]
2-8°C
| [solubility ]
freely sol hexane, chloroform, and most organic solvents;
insol water. | [form ]
solid | [pka]
4.75±0.70(Predicted) | [Water Solubility ]
Hydrolyzes in water. | [Hydrolytic Sensitivity]
7: reacts slowly with moisture/water | [Sensitive ]
Moisture Sensitive | [BRN ]
2424306 | [CAS DataBase Reference]
41879-39-4(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
UN 3259 8/PG 2
| [WGK Germany ]
3
| [F ]
10-21 | [TSCA ]
No | [HazardClass ]
8 | [PackingGroup ]
III |
| Hazard Information | Back Directory | [Physical properties]
mp 62–65°C; bp 87–90°C/40 mmHg. | [Uses]
O-(tert-Butyldimethylsilyl)hydroxylamine (tert-butyldimethylsilyl-O-hydroxylamine)is used to induce the cleavage, during solid supported synthesis of hydroxamic acids. It also finds it uses as a chemical additive and an intermediate. | [Preparation]
the reagents are most conveniently prepared
by treatment of hydroxylamine hydrochloride with
ethylenediamine in dichloromethane, followed by the appropriate
chlorosilane.A two-step procedure using ammonia in
place of ethylenediamine has also been reported. |
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