| Identification | More | [Name]
4'-(2-Methylpropyl)acetophenone | [CAS]
38861-78-8 | [Synonyms]
1-[4-(2-METHYLPROPYL)PHENYL]ETHANONE
1-(4-ISOBUTYLPHENYL)ETHAN-1-ONE
1-(4-ISOBUTYLPHENYL)ETHANONE
4'-ISOBUTYLACETOPHENONE
4-ISOBUTYLACETOPHENONE
IBUPROFEN IMP E
IBUPROFEN IMPURITY E
ISOBUTYL ACETOPHENONE
P-ISO-BUTYLACETOPHENONE
TIMTEC-BB SBB007668
1-[4-(2-methylpropyl)phenyl]-ethanon
Acetophenone, 4-isobutyl-
Ethanone, 1-[4-(2-methylpropyl)phenyl]-
4-Isobutylacetaphenone
1-[4-(2-methylpropyl)phenyl]ethan-1-one
1-(4-(2-METHYLPROPYL)PHENYL)ETNANONE
4'-(2-Methylpropyl)acetophenone
4-lsobutylacetophenone | [EINECS(EC#)]
254-159-8 | [Molecular Formula]
C12H16O | [MDL Number]
MFCD00027393 | [Molecular Weight]
176.25 | [MOL File]
38861-78-8.mol |
| Chemical Properties | Back Directory | [Boiling point ]
134-135°C 16mm | [density ]
0,952 g/cm3 | [vapor pressure ]
0.75Pa at 20℃ | [refractive index ]
1.5180 | [Fp ]
54°C | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
soluble in Dichloromethane; Diethyl Ether; Ethyl Acetate; THF | [form ]
neat | [color ]
Colorless to Yellow | [Water Solubility ]
Miscible with chloroform and methanol. Slightly miscible with water. | [BRN ]
1935275 | [InChI]
InChI=1S/C12H16O/c1-9(2)8-11-4-6-12(7-5-11)10(3)13/h4-7,9H,8H2,1-3H3 | [InChIKey]
KEAGRYYGYWZVPC-UHFFFAOYSA-N | [SMILES]
C(=O)(C1=CC=C(CC(C)C)C=C1)C | [LogP]
3.4 at 23℃ | [CAS DataBase Reference]
38861-78-8(CAS DataBase Reference) | [NIST Chemistry Reference]
| [EPA Substance Registry System]
38861-78-8(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R10:Flammable.
R40:Limited evidence of a carcinogenic effect. | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking .
S36:Wear suitable protective clothing .
S22:Do not breathe dust . | [RIDADR ]
1224 | [WGK Germany ]
3 | [TSCA ]
Yes | [HazardClass ]
3.2 | [PackingGroup ]
III | [HS Code ]
29143990 |
| Hazard Information | Back Directory | [Chemical Properties]
Clear Colourless Oil | [Uses]
A degradation product of Ibuprofen in tablets, which is a known toxin. Ibuprofen (I140000) impuritiy. | [Preparation]
Synthesis of 4-isobutylacetophenone: toluene and propylene are reacted with the participation of metal potassium, sodium carbonate and graphite, Alkylation on methyl to generate isobutylbenzene, Then with acetyl chloride in the participation of anhydrous aluminum trichloride to obtain the product.
 | [General Description]
4'-(2-Methylpropyl)acetophenone, also known as Ibuprofen EP Impurity E, is an impurity of ibuprofen. Ibuprofen is a nonsteroidal
anti-inflammatory drug (NSAID). It works by blocking your body's
production of certain natural substances that cause inflammation. |
|
|