Identification | Back Directory | [Name]
1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[biotinyl(polyethylene glycol)-2000] (aMMoniuM salt) | [CAS]
385437-57-0 | [Synonyms]
DSPE-PEG-2K-Biotin DSPE-PEG(2000) Biotin DSPE-MPEG-2000-Biotin DSPE-PEG-Biotin (MW 2000) 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[biotinyl(polyethylene glycol)-2000] (aMMoniuM salt) 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[biotinyl(polyethylene glycol)-2000] (aMMoniuM salt) ISO 9001:2015 REACH 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE-N-[BIOTINYL(POLYETHYLENE GLYCOL)-2000] (AMMONIUM SALT);DSPE-PEG(2000) BIOTIN | [Molecular Formula]
(C2H4O)nC54H101N4O12PS.Na | [MOL File]
385437-57-0.mol |
Hazard Information | Back Directory | [Description]
DSPE-PEG-Biotin, MW 2,000 is a biotin amphipilic material which forms micelles in an aqueous solution and binds selectively with streptavidin and avidin. This polymer is very promising nanocarriers for therapeutic drug delivery, imaging and molecular labeling. | [Uses]
DSPE-PEG-Biotin, MW 1000 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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