| Identification | Back Directory | [Name]
Folic acid PEG DSPE | [CAS]
1236288-25-7 | [Synonyms]
DSPE-PEG-5K-Folate
Folic acid PEG DSPE
DSPE-PEG(5000) Folate
DSPE-PEG(2000) Folate
Folic acid PEG DSPE ISO 9001：2015 REACH
1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[folate(polyethylene glycol)-5000] (aMMoniuM salt)
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-2000] (ammonium salt)
1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE-N-[FOLATE(POLYETHYLENE GLYCOL)-2000] (AMMONIUM SALT);DSPE-PEG(2000) FOLATE
1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE-N-[FOLATE(POLYETHYLENE GLYCOL)-5000] (AMMONIUM SALT);DSPE-PEG(5000) FOLATE | [Molecular Formula]
(C2H4O)nC63H104N9O15P.2H3N | [MOL File]
1236288-25-7.mol |
| Hazard Information | Back Directory | [Uses]
DSPE-PEG(5000) Folate may be used:
- in preparation of folate functionalized nanoparticles (NPs)
- in synthesis of BTPEPBI-containing nanoparticles
- in preparation of paclitaxel loaded folate modified lipid-shell and polymer-core nanoparticles (FLPNPs)
| [Biological Activity]
Folate receptors are cellular surface markers for numerous solid tumors. DSPE-PEG-folate (1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-5000]) incorporated into liposomes serves as a targeting ligand. Folate targeted drug delivery is useful in diagnosing and treating cancer and inflammatory diseases. Many molecules such as toxins (proteinaceous)immune stimulators and anti-cancer drugs can be delivered to folate receptor. |
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