| Identification | Back Directory | [Name]
Tenofovir Related Compound 6 | [CAS]
383365-04-6 | [Synonyms]
TAF-IM-A2
TAF Impurity E
Tenofovir Impurity 6
Tenofovir Impurity 48
Tenofovir Impurity 6-d6
enofovir Related Compound 6
Tenofovir Related Compound 6
Tenofovir Alafenamide Impurity 3
Tenofovir Alafenamide Impurity E
Tenofovir Alafenamide (R-Phosphine)
Tenofovir Alafenamide Diasteromer-1
Tenofovir Alafenamide Impurity 13 Monomer
9-[(R)-2-[[(S)-[[(S)-1-(isopropoxycarbonyl)ethyl]amino]-phenoxyphosphinyl]methoxy]propyl]adenine
isopropyl (((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-L-alaninate
N-[(R)-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-L-alanine 1-Methylethyl Ester
L-Alanine,N-[(R)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-, 1-methylethyl ester
(S)-isopropyl 2-(((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate | [Molecular Formula]
C21H29N6O5P | [MDL Number]
MFCD23704939 | [MOL File]
383365-04-6.mol | [Molecular Weight]
476.47 |
| Hazard Information | Back Directory | [Uses]
(S)-Isopropyl 2-(((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate is an isomer of Tenofovir Alafenamide (T018555), is a prodrug of Tenofovir (T018500). | [Definition]
ChEBI: Tenofovir alafenamide is an L-alanine derivative that is isopropyl L-alaninate in which one of the amino hydrogens is replaced by an (S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl group. A prodrug for tenofovir, it is used (as the fumarate salt) in combination therapy for the treatment of HIV-1 infection. It has a role as an antiviral drug, a HIV-1 reverse transcriptase inhibitor and a prodrug. It is a L-alanine derivative, a phosphoramidate ester, an ether, a member of 6-aminopurines and an isopropyl ester. It is functionally related to an adenine. It is a conjugate base of a tenofovir alafenamide(1+). |
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