| Identification | More | [Name]
5-Bromo-2-methoxyphenol | [CAS]
37942-01-1 | [Synonyms]
3-HYDROXY-4-METHOXYBROMOBENZENE
5-BROMO-2-METHOXYPHENOL
5-Brom-2-methoxy-phenol
4-Bromo-2-hydroxyanisole | [EINECS(EC#)]
609-492-7 | [Molecular Formula]
C7H7BrO2 | [MDL Number]
MFCD00673137 | [Molecular Weight]
203.03 | [MOL File]
37942-01-1.mol |
| Chemical Properties | Back Directory | [Melting point ]
64-70 | [Boiling point ]
150 °C / 20mmHg | [density ]
1.585±0.06 g/cm3(Predicted) | [storage temp. ]
Store Cold | [form ]
powder to crystal | [pka]
9.01±0.10(Predicted) | [color ]
White to Almost white | [Detection Methods]
HPLC | [InChIKey]
OLSJHVZRUFFIPL-UHFFFAOYSA-N | [CAS DataBase Reference]
37942-01-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [Hazard Note ]
Irritant/Store Cold | [HazardClass ]
IRRITANT | [HS Code ]
29095000 |
| Hazard Information | Back Directory | [Chemical Properties]
White to off-white crystal | [Uses]
The 5-Bromo-2-methoxyphenol is the important intermediate of producing depressor aliskiren. | [Synthesis]
The 5-bromo-2-methoxyphenol is synthesized by virtue of three steps of reactions as follows: by taking o-methoxyphenol as the raw materials, performing acetylation protection on the phenolic hydroxyl by use of acetic anhydride, and then performing bromination by use of bromine under the catalysis of iron powder, and finally performing deacetylation. |
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