| Identification | More | [Name]
N-Boc-D-proline | [CAS]
37784-17-1 | [Synonyms]
BOC-D-PRO
BOC-D-PROLINE
BOC-D-PROLINE-OH
BOC-D-PRO-OH
BOC-D-PYRD(2)-OH
BOC-(R)-PYRROLIDINE-5-CARBOXYLIC ACID
N-ALPHA-T-BOC-D-PROLINE
N-ALPHA-T-BUTYLOXYCARBONYL-D-PROLINE
N-ALPHA-T-BUTYLOXYCARBONYL-D-PYRROLIDINE-2-CARBOXYLIC ACID
N-ALPHA-TERT-BUTYLOXYCARBONYL-D-PROLINE
N-BOC-D-PROLINE
N-T-BOC-D-PROLINE
N-(TERT-BUTOXYCARBONYL)-D-PROLIN
N-(TERT-BUTOXYCARBONYL)-D-PROLINE
N-(TERT-BUTYLOXYCARBONYL)-D-PROLINE
(R)-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER
T-BUTYLOXYCARBONYL-D-PROLINE
N-Boc-D-proline
N-BOC-D-PROLINE-OH
N-Boc-D-proline, 98+% | [EINECS(EC#)]
1533716-785-6 | [Molecular Formula]
C10H17NO4 | [MDL Number]
MFCD00063226 | [Molecular Weight]
215.25 | [MOL File]
37784-17-1.mol |
| Chemical Properties | Back Directory | [Appearance]
White to off-white microcrystalline powder | [Melting point ]
134-137 °C (lit.) | [alpha ]
60 º (c=2, acetic acid) | [Boiling point ]
355.52°C (rough estimate) | [density ]
1.1835 (rough estimate) | [refractive index ]
60 ° (C=2, AcOH) | [storage temp. ]
−20°C
| [solubility ]
almost transparency in Acetic acid | [form ]
Crystalline Powder or Crystals | [pka]
4.01±0.20(Predicted) | [color ]
White to off-white | [optical activity]
[α]22/D +60°, c = 2 in acetic acid | [Detection Methods]
T,NMR,MS | [BRN ]
479316 | [InChI]
InChI=1S/C10H17NO4/c1-10(2,3)15-9(14)11-6-4-5-7(11)8(12)13/h7H,4-6H2,1-3H3,(H,12,13)/t7-/m1/s1 | [InChIKey]
ZQEBQGAAWMOMAI-SSDOTTSWSA-N | [SMILES]
N1(C(OC(C)(C)C)=O)CCC[C@@H]1C(O)=O | [CAS DataBase Reference]
37784-17-1(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
White to off-white microcrystalline powder | [Uses]
tert-Butoxycarbonyl-D-proline is Boc protected D-proline (P755990). It is used to prepare trichostatin A and trapoxin B analogs as histone deacetylase inhibitors. It is also used to prepare potent and selective nonpeptide inhibitors of caspases 3 and 7. | [reaction suitability]
reaction type: Boc solid-phase peptide synthesis |
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