| Identification | Back Directory | [Name]
MELITTIN | [CAS]
37231-28-0 | [Synonyms]
MELLITIN
MELITTIN
melittin-t
Melittinabout85%
Einecs 253-417-7
MELITTIN ABOUT 85%
MELITTIN (NATURAL)
melittinhoneybeevenom
MELITTIN FROM BEE VENOM
GIGAVLKVLTTGLPALISWIKRKRQQ-NH2
melittinfrombeevenomsequencing*grade
MELITTIN FROM BEE VENOM APPROX. 85%*BY H PLC
GLY-ILE-GLY-ALA-VAL-LEU-LYS-VAL-LEU-THR-THR-GLY-LEU-PRO-ALA-LEU-ILE-SER-TRP-ILE-LYS-ARG-LYS-ARG-GLN-GLN-NH2
H-GLY-ILE-GLY-ALA-VAL-LEU-LYS-VAL-LEU-THR-THR-GLY-LEU-PRO-ALA-LEU-ILE-SER-TRP-ILE-LYS-ARG-LYS-ARG-GLN-GLN-NH2 | [EINECS(EC#)]
253-417-7 | [Molecular Formula]
C131H229N39O31 | [MDL Number]
MFCD00076868 | [MOL File]
37231-28-0.mol | [Molecular Weight]
2846.46 |
| Chemical Properties | Back Directory | [Definition]
A polypeptide
derived from bee venom that has strong antibacterial
activity, especially against Staphylococcus aureus
80 which is resistant to penicillin. It inhibits growth
of many Gram-positive and Gram-negative bacteria.
| [Appearance]
solid | [Melting point ]
>121°C (dec.) | [Fp ]
112 °C | [storage temp. ]
2-8°C
| [solubility ]
Water (Slightly) | [form ]
White to off-white powder. | [color ]
White to Light Yellow | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [optical activity]
-89.5221 | [Water Solubility ]
water: 1mg/mL | [Merck ]
13,5846 | [Uses]
Antirheumatic drug. |
| Hazard Information | Back Directory | [Chemical Properties]
solid | [Biological Activity]
Cell permeable: no''Product does not compete with ATP.''Reversible: no''Target IC50: 5-7 μM 5-7 μM for activating phospholipase A2 and inhibits protein kinase C |
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