| Identification | More | [Name]
2,4-Difluorophenol | [CAS]
367-27-1 | [Synonyms]
2,4-DIFLUOROPHENOL
Phenol, 2,4-difluoro-
2,4-Difluorophenol, 98+%
2,4-Difluorophenol, 99+%
2,4-Difluorophenol 98% | [EINECS(EC#)]
206-688-0 | [Molecular Formula]
C6H4F2O | [MDL Number]
MFCD00009715 | [Molecular Weight]
130.09 | [MOL File]
367-27-1.mol |
| Chemical Properties | Back Directory | [Appearance]
clear yellow-green liquid after melting | [Melting point ]
22.4 °C (lit.) | [Boiling point ]
52-53 °C/19 mmHg (lit.) | [density ]
1.362 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.486(lit.)
| [Fp ]
134 °F
| [storage temp. ]
Flammables area | [pka]
8.72±0.18(Predicted) | [Specific Gravity]
1.362 | [Water Solubility ]
slightly soluble | [BRN ]
1934803 | [InChIKey]
NVWVWEWVLBKPSM-UHFFFAOYSA-N | [CAS DataBase Reference]
367-27-1(CAS DataBase Reference) | [NIST Chemistry Reference]
2,4-Difluorophenol(367-27-1) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi,C,F | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R37/38:Irritating to respiratory system and skin .
R41:Risk of serious damage to eyes.
R34:Causes burns.
R11:Highly Flammable.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
1992 | [WGK Germany ]
3
| [Hazard Note ]
Harmful | [HazardClass ]
3 | [PackingGroup ]
III | [HS Code ]
29081900 |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
2,4-Dichloronitrobenzene-->2,5-Difluorophenol-->1,4-Difluorobenzene | [Preparation Products]
3-(2,4-difluorophenoxy)propanoic acid-->3-AMINO-2-(2,4-DIFLUOROPHENOXY)PYRIDINE-->2,4-DIFLUORO-6-NITROPHENOL-->2,4-Difluoro-5-nitrophenol-->2-Bromo-4,6-difluorophenol-->ABBV-075-->4-Fluorophenol-->AKOS B013914-->3-Ethoxy-2,6-difluorobenzaldehyde-->2-(2,4-difluorophenoxy)aniline-->4'-(2,4-DIFLUOROPHENOXY)ACETOPHENONE-->7,9-difluoro-2,3,4,5-tetrahydro-1-benzoxepin-5-one |
| Hazard Information | Back Directory | [Chemical Properties]
clear yellow-green liquid after melting | [Uses]
2,4-Difluorophenol, is an organic building block used for the synthesis of various pharmaceutical compounds, such as antivirulence agents. It is also used in the synthesis of new α-Phenoxyacetamide derivatives, acting as type III secretion system of Pseudomonas aeruginosa PAO1, a gram-negative bacteria. |
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