| Identification | Back Directory | [Name]
S(-)-VERAPAMIL | [CAS]
36622-28-3 | [Synonyms]
LU 33926
S(-)-VERAPAMIL
S-Verapamil HCL
S(-)-VERAPAMIL HYDROCHLORIDE
S(-)-VERAPAMIL HYDROCHLORIDE HYDRATE
S(-)-Verapamil hydrate hydrochloride
[7-cyano-1,7-bis(3,4-dimethoxyphenyl)nonan-3-yl]ammonium chloride
(-)-[3-cyano-3-(3,4-dimethoxyphenyl)hex-6-yl][2-(3,4-dimethoxyphenyl)ethyl]methylammonium chloride
(2S)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile:hydrochloride
Benzeneacetonitrile, a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-, monohydrochloride, (S)-
Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl) ethyl]methylamino]propyl]-3,4-dimethoxy -α-(1-methylethyl)-, monohydrochloride, (αS)-
Benzeneacetonitrile, a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-, monohydrochloride, (aS)- (9CI) | [EINECS(EC#)]
253-132-8 | [Molecular Formula]
C27H38N2O4 | [MDL Number]
MFCD00869809 | [MOL File]
36622-28-3.mol | [Molecular Weight]
454.6 |
| Chemical Properties | Back Directory | [Melting point ]
131-133 °C | [solubility ]
H2O: >30 mg/mL
| [form ]
solid
| [color ]
white
| [optical activity]
[α]22/D 6.1°, c = 0.1 in ethanol(lit.) | [Water Solubility ]
H2O: >30mg/mL
ethanol: soluble |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
Both isomers inhibit the p-glycoprotein efflux pump in multidrug resistant tumor cells. | [Definition]
ChEBI:(S)-verapamil hydrochloride is a hydrochloride salt resulting from the reaction of equimolar amounts of (S)-verapamil and hydrogen chloride. It is an enantiomer of a dexverapamil hydrochloride. | [Biochem/physiol Actions]
Active enantiomer of (±)-verapamil. Ca2+ channel (L-type) modulator; adrenoceptor antagonist; cardiac depressant. |
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