| Identification | Back Directory | [Name]
(3,4-Dimethoxyphenyl)isopropyl ketone | [CAS]
14046-55-0 | [Synonyms]
Nsc63844
Verapamil Impurity L
Verapamil EP Impurity L
verapamil impurities879
3',4'-Dimethoxyisobutyrophenone
Isobutyrophenone, 3',4'-dimethoxy-
1-(3,4-Dimethoxyphenyl)-2-methylpro
Verapamil Hydrochloride EP Impurity L
(3,4-Dimethoxyphenyl)isopropyl ketone
3',4'-DIMETHOXY-2-METHYLPROPIOPHENONE
1-(3,4-Dimethoxyphenyl)-2-methyl-1-propanone
1-Propanone, 1-(3,4-dimethoxyphenyl)-2-methyl-
Verapamil Impurity 12（Verapamil EP Impurity L） | [Molecular Formula]
C12H16O3 | [MDL Number]
MFCD01718113 | [MOL File]
14046-55-0.mol | [Molecular Weight]
208.25 |
| Chemical Properties | Back Directory | [Boiling point ]
165-170℃ (10 Torr) | [storage temp. ]
Refrigerator, under inert atmosphere | [solubility ]
Chloroform (Sparingly), Methanol (Slightly) | [form ]
Oil | [color ]
Colourless |
| Hazard Information | Back Directory | [Uses]
1-(3,4-Dimethoxyphenyl)-2-methyl-1-propanone (Verapamil EP Impurity L) is a compound being considered as an inhibitor of melanogenesis. It may reduce growth or pigment production in melanocyte cells. | [Preparation]
Preparation by acylation of veratrole,
with isobutyryl chloride in the presence of aluminium chloride (85%)
with isobutyric acid in the presence of PPA at 60° for 2.5 h
with isobutyric anhydride in acetonitrile in the presence of TiCl(OTf)3 /TfOH at r.t. for 12 h (89%). |
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BOC Sciences
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TOSUN PHARM
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www.toref.cn/ |
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