| Identification | More | [Name]
Azetidine hydrochloride | [CAS]
36520-39-5 | [Synonyms]
AZETIDINE HCL
AZETIDINE HYDROCHLORIDE
TRIMETHYLENEIMINE HYDROCHLORIDE
Azetidine (trimethyleneimine) hydrochloride
Azetidine hydrochloride ,99% | [EINECS(EC#)]
627-415-5 | [Molecular Formula]
C3H8ClN | [MDL Number]
MFCD00191762 | [Molecular Weight]
93.56 | [MOL File]
36520-39-5.mol |
| Chemical Properties | Back Directory | [Appearance]
White powder | [Melting point ]
>300 °C(lit.)
| [Fp ]
152 °C | [storage temp. ]
Inert atmosphere,2-8°C | [form ]
powder to crystal | [color ]
White to Almost white | [Water Solubility ]
Soluble in water (103.8°C at 760 mmHg). | [Sensitive ]
Hygroscopic | [Detection Methods]
T,NMR,MS | [InChI]
InChI=1S/C3H7N.ClH/c1-2-4-3-1;/h4H,1-3H2;1H | [InChIKey]
HGQULGDOROIPJN-UHFFFAOYSA-N | [SMILES]
C1CNC1.Cl | [CAS DataBase Reference]
36520-39-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
UN1325 | [WGK Germany ]
3
| [HazardClass ]
IRRITANT, HYGROSCOPIC | [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
Azetidine hydrochloride is a four-membered ring nitrogen-containing heterocycle. Useful building block in the synthesis of polypeptides and other nitrogen containing compounds with potential biological properties.
| [Uses]
Basic building block for synthesizing azetidines.1,2 | [General Description]
Azetidine derivatives are an essential class of aza-heterocyclic compounds with various biological activities and have been widely used as building blocks in pharmacological research. Although azetidine has the simplest structure, it is only commercially available in small quantities and at a high price. In addition, this compound is hard to synthesize for several reasons, such as cyclization of the four-membered ring, stability of the ring, and low boiling point[1]. | [References]
[1] Jian Sun, Qi Sun, S. Gong. “A Novel Strategy for the Synthesis of Azetidine.” Advanced Materials Research 6 1 (2013): 135–138.
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