| Identification | More | [Name]
N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt hydrate | [CAS]
357166-30-4 | [Synonyms]
N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt hydrate
Pemetrexed disodium hydrate | [EINECS(EC#)]
814-356-7 | [Molecular Formula]
2(C20H19N5Na2O6).5(H2O) | [MDL Number]
MFCD13194950 | [Molecular Weight]
1032.84 | [MOL File]
357166-30-4.mol |
| Hazard Information | Back Directory | [Uses]
Pemetrexed Disodium Hydrate is an chemotherapy drug for the treatment of pleural mesothelioma and non-small cell lung cancer. Pemetrexed Disodium Hydrate exhibit inhibitory activities towards thymidyl
ate synthase as well as other folate dependent enzymes. | [in vivo]
The group of mice treated with PC61 plus Pemetrexed demonstrates statistically longer survival than other groups. In a survival analysis, significantly better survival is observed in the group of mice treated with PC61 plus Pemetrexed compare with those treated with PC61 alone, rat IgG plus Pemetrexed, or no treatment[2]. | [storage]
Store at -20°C |
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