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ChemicalBook--->CAS DataBase List--->339163-65-4

339163-65-4

339163-65-4 Structure

339163-65-4 Structure
IdentificationBack Directory
[Name]

troponin I type 3 (cardiac)
[CAS]

339163-65-4
[Synonyms]

CMH7
RCM1
cTnI
CMD2A
CMD1FF
RCM 1 NEW
Troponin I ELISA Kit
troponin I type 3 (cardiac)
Anti-TNNI3 antibody produced in goat
Monoclonal Anti-TNNI3 antibody produced in mouse
3-Pyridinecarbonitrile, 2-[[2-oxo-2-(2-thienyl)ethyl]thio]-4,6-di-2-thienyl-
[Molecular Formula]

C20H12N2OS4
[MDL Number]

MFCD00742440
[MOL File]

339163-65-4.mol
[Molecular Weight]

424.58
Chemical PropertiesBack Directory
[Boiling point ]

632.8±55.0 °C(Predicted)
[density ]

1.49±0.1 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Inert atmosphere,Room temperature
[solubility ]

DMSO : 16.67 mg/mL (39.26 mM)
[form ]

buffered aqueous solution
[pka]

-1.42±0.37(Predicted)
[color ]

Off-white to gray
[biological source]

mouse
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319
[Precautionary statements ]

P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362
Hazard InformationBack Directory
[General Description]

Troponin I3, cardiac type (TNNI3), also known as cardiac troponin I (cTnI), is the inhibitory element of troponin. It possesses an inhibitory peptide (IP) domain and a switch peptide (SP) domain that is located N-terminal of the IP domain. The gene encoding TNNI3 is localized on human chromosome 19q13.42.
[Biochem/physiol Actions]

Troponin I3, cardiac type (TNNI3) or cardiac troponin I (cTnI) modulates the diastolic function of the heart. Low expression of TNNI3 is associated with cardiac diastolic dysfunction. Elevated expression of the protein indicates cardiac injury. TNNI3 is a biomarker for myocardial infarction and mutations in the gene encoding it have been linked to hypertrophic cardiomyopathy.
[storage]

Store at -20°C
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