Identification | Back Directory | [Name]
Nicarbazin | [CAS]
330-95-0 | [Synonyms]
mk75 nicarb nicoxin nirazin Nicarzin nicrazin nicrazine nicarbazi NICARBAZIN NICARBAZINE NICARBAZINUM n,n’-bis(4-nitro Nicarbazine Pure 1,3-bis(4-nitrophenyl)urea-4,6-dimethylpyrimidin-2-ol (1:1) carbanilide,4,4’-dinitro-,compd.with4,6-dimethyl-2-pyrimidinol(1:1) n,n’-bis(4-nitrophenyl)ureacompd.with4,6-dimethyl-2-pyrimidinol(1:1) N,N'-BIS(4-NITROPHENYL)UREA COMPOUND WITH 4,6-DIMETHYL-2-PYRIMIDINONE urea,n,n’-bis(4-nitrophenyl)-,compd.with4,6-dimethyl-2(1h)-pyrimidinone( Urea, N,N-bis(4-nitrophenyl)-, compd. with 4,6-dimethyl-2(1H)-pyrimidinone (1:1) Nicarbazin,N,N′-bis(4-Nitrophenyl)urea compound with 4,6-dimethyl-2-pyrimidinone | [EINECS(EC#)]
206-359-1 | [Molecular Formula]
C19H18N6O6 | [MDL Number]
MFCD00867204 | [MOL File]
330-95-0.mol | [Molecular Weight]
426.38 |
Hazard Information | Back Directory | [Chemical Properties]
Forms crystals.Insoluble in water | [Biochem/physiol Actions]
Nicarbazin, an effective anticoccidial, is also a wide-spectrum anti-parasitic drug. It affects avian reproduction by reducing egg production, egg weight, and egg hatchability. The mechanism of action of Nicarbazin is unknown. | [Mode of action]
Nicarbazin interferes with the formation of the vitelline membrane, separating the egg yolk and egg white. The exact mode of action is unknown, although it is thought nicarbazin interferes with cholesterol metabolism in the formation of the membrane. Eggs from treated birds are described as mottled in appearance, reflecting a porous vitelline membrane. The effect on hatchability is a function of time and dose and the effect is reversible. |
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