Identification | Back Directory | [Name]
Moroxydine hydrochloride | [CAS]
3160-91-6 | [Synonyms]
virustat spenitol virusmin flumidin Virus spirit Moroxydine hyd MOROXYDINE HCL abobhydrochloride TIMTEC-BB SBB009855 Moroxydine Hydrochlo Moroxydine hydrochlorid MOROXYDINE HYDROCHLORIDE MoroxydineHydrochloride> MORPHOLINO-BIUANIDE HYDROCHLORIDE MORPHOLINO-BIGUANIDE HYDROCHLORIDE Moroxydine hydrochloride USP/EP/BP Moroxydine hydrochloride Solution, 100ppm 1-morpholinocarbonimidoylguanidine hydrochloride n-amidino-4-morpholinecarboxamidinmonohydrochloride 1,1-anhydrobis(beta-hydroxyethyl)-biguanidhydrochloride N-CarbaMiMidoylMorpholine-4-carboxiMidaMide hydrochloride Guanidine,N-(amino-4-morpholinylmethyl)-, hydrochloride (1:1) N-(AMINOIMINOMETHYL)-4-MORPHOLINECARBOXIMIDAMIDE HYDROCHLORIDE n-(aminoiminomethyl)-4-morpholinecarboximidamidmonohydrochloride n(sup1),n(sup1)-anhydrobis(beta-hydroxyethyl)biguanidehydrochloride 4-Morpholinecarboximidamide, N-(aminoiminomethyl)-,monohydrochloride N-(aminoiminomethyl)-4-morpholinecarboximidamide,hydrochloride (1:1) N-Carbamimidoylmorpholine-4-carboximidamide hydrochloride[ABOB Hydrochloride | [EINECS(EC#)]
221-612-6 | [Molecular Formula]
C6H14ClN5O | [MDL Number]
MFCD00012798 | [MOL File]
3160-91-6.mol | [Molecular Weight]
207.66 |
Chemical Properties | Back Directory | [Melting point ]
211-214 °C(lit.)
| [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
DMSO (Very Slightly, Heated), Water (Slightly) | [form ]
Solid | [color ]
Off-White | [Merck ]
14,6272 | [InChIKey]
FXYZDFSNBBOHTA-UHFFFAOYSA-N |
Hazard Information | Back Directory | [Originator]
Grippe,Nissin | [Uses]
Moroxydine hydrochloride is an antiviral used against a number of RNA and DNA viruses.
| [Manufacturing Process]
43.5 g morpholine, 41.7 ml concentrated hydrochloric acid, 40 ml of water,
and 42 g dicyandiamide are refluxed for 48 hours, whereupon the reaction
mixture is cooled to +5°C and filtered. The filtrate is evaporated to dryness
and extracted and extracted with boiling ethanol. Yield: 50 g. The formed 4-
morpholinecarboximidoylguanidine hydrochloride is purified by recrystallization
from methanol. The salt may be converted into the base by adding equivalent
of any basic compound (triethylamine, sodium bicarbonate and so on). In practice it is usually used as hydrochloride. | [Therapeutic Function]
Antiviral | [General Description]
Determination of moroxydine hydrochloride in Gan Mao Qing capsules by derivative spectrophotometric signal multiplier method has been reported. Therapeutical efficiency of moroxidine hydrochloride against herpes virus induced keratoconjunctivitis has been evaluated by immunofluorescence techniques. | [storage]
Store at -20°C |
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