| Identification | Back Directory | [Name]
2-naphthoylethyltrimethylammonium | [CAS]
31059-54-8 | [Synonyms]
Α-NETA
β-NETA
2-naphthoylethyltrimethylammonium
2-(beta-Naphthoyl)ethyltrimethylammonium iodide
2-Dimethylaminoethyl 2-naphthyl ketone methiodide
trimethyl-(3-naphthalen-2-yl-3-oxopropyl)azanium:iodide | [Molecular Formula]
C16H20NO.I | [MOL File]
31059-54-8.mol |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C, protect from light, stored under nitrogen | [solubility ]
DMSO: 3mg/ml; Methanol: Soluble | [form ]
A solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
Choline acetyltransferase (ChAT) mediates the synthesis of the neurotransmitter acetylcholine from acetyl-CoA and choline. In addition to its critical role in neurosignaling, deficiencies in ChAT are linked to congenital myasthenic syndromes, Alzheimer’s disease, and multiple sclerosis. α-NETA is a stable, non-competitive, and slowly reversible inhibitor of ChAT (IC50 = 9 μM). This naturally fluorescent compound is a poor inhibitor of cholinesterases and carnitine acetyltransferase. α-NETA is commonly used in cells in culture. | [Uses]
Choline acetyltransferase (ChAT) mediates the synthesis of the neurotransmitter acetylcholine from acetyl-CoA and choline. In addition to its critical role in neurosignaling, deficiencies in ChAT are linked to congenital myasthenic syndromes, Alzheimer’s disease, and multiple sclerosis. α-NETA is a stable, non-competitive, and slowly reversible inhibitor of ChAT (IC50 = 9 μM). This naturally fluorescent compound is a poor inhibitor of cholinesterases and carnitine acetyltransferase. α-NETA is commonly used in cells in culture.[Cayman Chemical] | [storage]
Store at -20°C, protect from light, stored under nitrogen |
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